Enhancement and Demyefination of the Intraorbital Optic Nerve: Fat Suppression Magnetic Resonance Imaging
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2022, European Journal of RadiologyCitation Excerpt :It is surrounded by high contrast fat; prone to chemical shift artefacts due to sleeve of CSF and is closely approximated to the proton-deficient bone in its canalicular segment; all of which impose a challenge to its characterization. This drove earlier approaches to evaluate ON that revolved around 2D STIR and 2D-FS, which have employed section thicknesses of 3–4 mm [10,11]. Studies focusing on sequences capable of suppressing fluid, fat and normal WM using FLAIR and DIR were conducted which showed their usefulness in identifying demyelinating lesions [12].
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2011, NeurologyCitation Excerpt :Our results are in agreement with another study that also used unselected patients.19 Our detection rate of 63% of the optic nerve lesion is somewhat lower than most other studies.4,5,20–25 The choice of MRI sequence was based on clinical experience whereas other studies have focused more on identification rate when choosing MRI sequences, some with the use of triple-dose gadolinium.4
Supported in part by an unrestricted departmental grant from Research to Prevent Blindness, Inc, New York, New York.