Cell
Volume 110, Issue 5, 6 September 2002, Pages 537-540
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Translating Axon Guidance Cues

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Abstract

Recent studies suggest that local translation of mRNA within axons plays a key role in two aspects of growth cone navigation. One line of evidence implies a local synthesis of proteins that mediate growth cone collapse and turning in response to guidance cues; another indicates that growth cones possess the machinery that would allow the local synthesis of receptors for axon guidance cues.

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