Two distinct types of AMPA responses in cultured rat hippocampal neurons
References (14)
- et al.
Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit
Neuron
(1992) - et al.
Excitatory synapse in the rat hippocampus in tissue culture and effects of aniracetam
Neurosci. Res.
(1991) - et al.
Functional expression from cloned cDNAs of glutamate receptor species responsive to kainate and quisqualate
FEBS Lett.
(1990) - et al.
Molecular cloning and functional expression of glutamate receptor subunit gene
Science
(1990) - et al.
Ca2+ permeability of KA-AMPA-gated glutamate receptor channels depends on subunit composition
Science
(1991) - et al.
Cloning by functional expression of a member of the glutamate receptor family
Nature
(1989) - et al.
Identification of a site in glutamate receptor subunits that controls calcium permeability
Science
(1991)
Cited by (43)
Homer1a regulates the activity-induced remodeling of synaptic structures in cultured hippocampal neurons
2007, NeuroscienceCitation Excerpt :It was found that the activity-induced temporal changes of synaptophysin and synapsin were similar to that of synaptotagmin, suggesting that glutamate stimulation also induces the structural changes at presynaptic sites. In hippocampal neurons, AMPA receptors are responsible for most fast excitatory neurotransmission, and GluR2 is known to be a major component of the receptors (Ozawa and Iino, 1993). Expression of surface GluR2 plays an important role in synaptic transmission.
A novel method for monitoring the cell surface expression of heteromeric protein complexes in dispersed neurons and acute hippocampal slices
2007, Journal of Neuroscience MethodsCurrent perspectives on NMDA-type glutamate signalling in bone
2007, International Journal of Biochemistry and Cell BiologyDifferential redistribution of native AMPA receptor complexes following LTD induction in acute hippocampal slices
2007, NeuropharmacologyCitation Excerpt :GluR2-containing AMPARs have low Ca2+ permeability and consequently display outwardly rectifying current–voltage (I–V) relationships, whereas GluR2-lacking AMPARs have high Ca2+ permeability and are inwardly rectifying (Hollmann et al., 1991; Burnashev et al., 1992). In hippocampal neurons AMPARs comprise mainly GluR2 (Ozawa and Lino, 1993) with either GluR1 (GluR1/2) or GluR3 (GluR2/3), although there is evidence for GluR1 homomers and GluR2-lacking heteromers (Wenthold et al., 1996). Based on experiments using recombinant subunits it has been proposed that GluR1/2 complexes are driven into synapses during hippocampal long-term potentiation (LTP), whereas GluR2/3 complexes are continuously inserted into synapses regardless of activity (Shi et al., 2001).