Trends in Genetics
Volume 10, Issue 12, December 1994, Pages 436-440
Journal home page for Trends in Genetics

Review
GAPs for rho-related GTPases

https://doi.org/10.1016/0168-9525(94)90114-7Get rights and content

Abstract

Ras-related GTP-binding proteins (GTPases) of the rbo subfamily play important roles in regulating the organization of the actin cytoskeleton. A large number of multifunctional proteins that can stimulate their intrinsic GTPase activity have been identified. Here, we discuss the nature of such GTPase-activating proteins (GAPs) and their potential importance for cell signalling.

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