Localization and anatomical identification of theta and complex spike cells in dorsal hippocampal formation of rats
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Cited by (186)
Persistent sexually dimorphic effects of adolescent THC exposure on hippocampal synaptic plasticity and episodic memory in rodents
2022, Neurobiology of DiseaseCitation Excerpt :For the LPP, aTHC had no effect on FF in males but modestly increased facilitation at 20 and 40 Hz (p < 0.05) in females (Fig. 4B,D; Suppl. Figs. 1D, 2D). Hippocampal and neocortical pyramidal cells commonly fire in high frequency bursts during learning behavior (Ranck Jr., 1973; Fox and Ranck, 1975). Stimulation trains that mimic this pattern produce a composite postsynaptic response that reflects presynaptic frequency facilitation and spatio-temporal summation of EPSPs in target dendrites (Larson et al., 1986).
The Role of the Posterior Hypothalamus in the Modulation and Production of Rhythmic Theta Oscillations
2021, NeuroscienceCitation Excerpt :Theta field oscillations can be broadly described as a result of rhythmic and synchronous activity of large groups of very specific neurons located in a given brain region. Rhythmically firing cells related to hippocampal theta oscillations were found in a number of different brain regions including the hippocampal formation (Green et al., 1960; Fox and Ranck, 1975; Bland et al., 1980; Colom and Bland 1987; Smythe et al., 1991; Konopacki et al., 2006; Kowalczyk et al., 2013; Kowalczyk et al., 2014), medial septum (Petsche et al., 1962; Apostol and Creutzfeldt, 1974; Brazhnik and Vinogradova, 1988; Ford et al., 1989; Colom et al., 1991; Bland et al., 1994), entorhinal cortex (Alonso and García-Austt, 1987; Dickson et al., 1994; Dickson et al., 1995), cingulate cortex (Colom et al., 1988), dorsal raphe (Kocsis and Vertes, 1992), pontine region (Hanada et al., 1999), red nucleus (Dypvik and Bland, 2004), and posterior hypothalamus (Kirk and McNaughton, 1991; Kocsis and Vertes, 1994; Bland et al., 1995; Kirk et al., 1996; Kirk, 1997; Bocian et al., 2016a; Caban et al., 2018). The firing pattern of these neurons, termed theta-related cells, is highly correlated with simultaneously recorded synchronous theta oscillations or asynchronous large irregular activity (LIA; Fig. 1).
Normal CA1 Place Fields but Discoordinated Network Discharge in a Fmr1-Null Mouse Model of Fragile X Syndrome
2018, NeuronCitation Excerpt :Single units were classified as complex-spike or theta cells according to published criteria (Fenton et al., 2008; Ranck, 1973) (Figure S3). Complex-spike cells appear to be pyramidal cells, whereas theta cells are likely local interneurons (Fox and Ranck, 1975). Pyramidal cells were judged to have long-duration waveforms (>250 μs), low discharge rate (<2 AP/s) and a tendency to fire in bursts (peak inter-spike interval < 10 ms).
Place cells and long-term potentiation in the hippocampus
2017, Neurobiology of Learning and MemoryThe representation of space in the brain
2017, Behavioural ProcessesHippocampal sharp waves and ripples: Effects of aging and modulation by NMDA receptors and L-type Ca<sup>2+</sup> channels
2015, NeuroscienceCitation Excerpt :Additionally, scanning our long-lasting recordings of spontaneous activity we have detected single-cell activity occurring between SWR events in slices from both age groups (Fig. 3B). This complex spike bursting displayed several of the typical features of complex spike activity recorded in vivo from CA1 pyramidal cells (Ranck, 1973; Fox and Ranck, 1975, 1981; McNaughton et al., 1983; Suzuki and Smith, 1985; Harris et al., 2001) (see also Methods). We analyzed activity of complex spike cells that occurred during non-oscillatory periods, since identification of complex spike bursts during SWRs was not possible.
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Current address for both authors is: Dept. of Physiology, Downstate Medical Center, State University of New York, Brooklyn, New York 11203. Sally Wu and Jacqueline Smith helped in some of the early stages of the work. The technical assistance of Ann Maxwell was important throughout. This work was supported by grants from the National Institute of Mental Health (MH 12979), The National Science Foundation (GB 26184), and the National Institute of Health (NS-10970).