The frequency and distribution of medium-sized neurons with indented nuclei in the primate and rodent neostriatum

doi:10.1016/0006-8993(85)91524-0

Brain Research

Volume 327, Issues 1–2, 18 February 1985, Pages 307-311

https://doi.org/10.1016/0006-8993(85)91524-0 Get rights and content

Abstract

Nuclear morphology is known to distinguish two classes of medium-sized neurons in the neostriatum, spiny projection neurons which have an unindented nucleus and aspiny interneurons which exhibit enfoldings of their nuclear envelope. The frequency and distribution of medium-sized neostriatal neurons with indented nuclei were examined in the light microscope in semi-thick sections. Results showed that the proportion of neostriatal neurons with nuclear indentations was greater in the monkey (23%) than in the mouse and rat (4–5%). Also, nuclear enfoldings were found in more neurons of the monkey caudate than putamen, whereas in the rodent regional differences were not observed. Findings suggest that aspiny interneurons play a greater role in the integrative and functional organization of the neostriatum in the primate than in the rodent brain.

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: This work was supported by National Institutes of Health Grants NS 16367 (M.D.).

^*: The assistance of Ms. Janice Carey and Ms. Kathleen Sullivan is greatly appreciated.

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The frequency and distribution of medium-sized neurons with indented nuclei in the primate and rodent neostriatum

Abstract

Neuroscience

Brain Research

Neuroscience

Biol. Cell.

A type of aspiny neuron in the rat neostriatum accumulates [3H]γ-aminobutyric acid: combination of Golgi-staining, autoradiography, and electron microscopy

J. comp. Neurol.

Localization of substance P-like immunoreactivity in nerve terminals in the neostriatum of the rat: a correlated light and electron microscopic study

J. Neurocytol.

A Golgi study of rat neostriatal neurons: light microscopic analysis

J. comp. Neurol.

Uptake of [3H]taurine into medium-size neurons and into identified stratonigral neurons in the rat neostriatum

Brain Research

Ultrastructure of Golgi-impregnated and gold-toned spiny and aspiny neurons in the monkey neostriatum

J. Neurocytol.

Ultrastructural features of immunoreactive somatostatin neurons in the rat caudate nucleus

J. Neurosci.

Light and electron microscopic localization of immunoreactive leu-enkephalin in the monkey basal ganglia

J. Neurosci.

A type of aspiny neuron in the rat neostriatum accumulates [³H]γ-aminobutyric acid: combination of Golgi-staining, autoradiography, and electron microscopy

Uptake of [³H]taurine into medium-size neurons and into identified stratonigral neurons in the rat neostriatum