A reinvestigation of the analgesic effects induced by stimulation of the periaqueductal gray matter in the rat. II. Differential characteristics of the analgesia induced by ventral and dorsal PAG stimulation
References (100)
- et al.
Serotonergic and non-serotonergic neurons of the dorsal raphé: reciprocal changes in firing induced by peripheral nerve stimulation
Brain Research
(1978) - et al.
Analgesia induced by microinjection of morphine into and electrical stimulation of the nucleus reticularis paragigantocellularis of rat medulla oblongata
Neuropharmacology
(1978) - et al.
Monoaminergic mechanisms of stimulation-produced analgesia
Brain Research
(1975) - et al.
Antagonism of stimulation-produced analgesia by p-CPA, a serotonin synthesis inhibitor
Brain Research
(1972) - et al.
Reversal of morphine and stimulation-produced analgesia by subtotal spinal cord lesions
Pain
(1977) - et al.
Unilateral 5,7-dihydroxytryptamine lesions of the dorsal raphénucleus (DRN) and rat rotational behaviour
Europ. J. Pharmacol.
(1980) - et al.
Stress-induced analgesia: neutal and hormonal determinants
Neurosci. Biobehav. Rev.
(1980) - et al.
Evidence for opioid and non-opioid forms of stimulation-produced analgesia in the rat
Brain Research
(1982) - et al.
Conditional fear-induced antinociception and decreased binding of [3H]N-Leu-enkephalin to rat brain
Brain Research
(1978) - et al.
Ascending projections to nucleus parafascicularis of the cat
Brain Research
(1981)
Stimulation-produced analgesia in rats: assessment by two pain tests and correlation with self-stimulation
Exp. Neurol.
Periaqueductal grey stimulation: an association between selective inhibition of dorsal horn neurons and changes in peripheral circulation
Pain
Role of the nucleus raphémagnus in opiate analgesia as studied by the microinjection technique in the rat
Brain Research
A reinvestigation of the analgesic effects induced by stimulation of the periagueductal gray matter in the rat. I. The production of behavioral side effects together with analgesia
Brain Research
An evaluation of stimulation-produced analgesia in the cat
Exp. Neurol.
Biochemical and behavioural effects of serotonin neurotoxins on the nigrostriatal dopamine system: comparison of injection sites
Brain Research
Inhibition of visceral pain by electrical stimulation of the periaqueductal gray matter
Pain
Suppression by LSD of the inhibitory effect exerted by dorsal raphéstimulation on certain spinal cord interneurons in the cat
Brain Research
Effects of midbrain central gray matter lesions on escape-avoidance behavior in rats
Physiol. Behav.
Reduction of stimulation-produced analgesia by lysergic acid diethylamide, a depressor of serotoninergic neural activity
Brain Research
Behavioral and physiological studies of non-narcotic analgesia in the rat elicited by certain environmental stimuli
Brain Research
A quantitative rotational model for studying serotonergic function in the rat
Brain Research
The projection from nucleus raphémagnus and other brainstem nuclei to the spinal cord in the rat: a study using the HRP blue-reaction
Neurosci. Lett.
Morphine-induced and stimulation-produced analgesias at coincident periaqueductal central gray loci: evaluation of analgesic congruence, tolerance and cross-tolerance
Exp. Neurol.
Mesencephalic central gray lesions and fear-motivated behavior in rats
Brain Research
Self-stimulation loci in the midbrain central gray matter of the rat
Behav. Biol.
Pain reduction by focal electrical stimulation of the brain: an anatomical and behavioral analysis
Brain Research
Peripheral somatic activation and spontaneous firing patterns in the periqueductal gray of the cat
Neurosci. Lett.
Interactions between serotonergic and dopaminergic systems in rat brain demonstrated by small unilateral lesions of the raphénuclei
Europ. J. Pharmacol.
A map of serotoninergic structures involved in stimulation producing analgesia in unrestrained freely moving cats
Brain Research
Analgesia induced by electrical stimulation of the inferior centralis nucleus of the raphéin the cat
Pain
Comparison between naloxone reversal of morphine and electrical stimulation induced analgesia in the rat mesencephalon
Life Sci.
Raphémagnus lesions disrupt stimulation-produced analgesia from ventral but not dorsal midbrain areas in the rat
Brain Research
Morphine analgesia: blockade by raphémagnus lesions
Brain Research
Periventricular system lesions and stimulation produced analgesia
Pain
Analgesia from rostral brain stem stimulation in the rat
Brain Research
Differential effecs of noxious and non-noxious input on neurones according to location in ventral periaqueductal grey or dorsal raphénucleus
Brain Research
Effects aversifs et appétitifs induits par stimulation mésencephalique et hypothalamique
Brain Research
Etude des systèmes de renforcement négatif et de renforcement positif au niveau de la substance grise centrale chez le rat
Physiol. Behav.
Analgesia and hyperreactivity produced by intracranial microinjections of morphine into the periaqueductal gray matter of the rat
Behav. Biol.
Afferent projections to affective attack sites in cat hypothalamus
Brain Research
Blockade by naltrexone of analgesia produced by stimulation of the dorsal raphénucleus
Pharmacol. Biochem. Behav.
Mesencephalically induced escape behavior and avoidance performance
Exp. Neurol.
The somatotopic organization of the nucleus raphémagnus and surrounding brain stem structures as revealed by HRP slow-release gels
Brain Research
A possible role for the dorsal periventricular catecholamine bundle in stimulation produced analgesia: a behavioral and histochemical study
Brain Research
Motivational effects of electrical stimulation in dorsal tegmentum of the rat
Physiol. Behav.
Narcotic analgestics: CNS sites and mechanisms of action as revealed by intracerebral injection techniques
Pain
An inability to anatagonize with naloxone the elevated nociceptive thresholds resulting from electrical stimulation of the mesencephalic central gray
Life Sci.
Concurrent mapping of brain sites for sensitivity of the direct application of morphine and focal electrical stimulation in the production of antinociception in the rat
Pain
Serotonergic projections to the caudal brain stem: a double label study using horseradish peroxidase and serotonin immunocytochemistry
Brain Research
Cited by (143)
Cell type-specific dissection of sensory pathways involved in descending modulation
2023, Trends in NeurosciencesDetailed organisation of the human midbrain periaqueductal grey revealed using ultra-high field magnetic resonance imaging
2023, NeuroImageCitation Excerpt :It has been argued that this analgesic response facilitates the successful execution of confrontation (fight) or escape (flight), by preventing the potential interruption of the “conscious appreciation” of the pain state (Keay and Bandler, 2002). It is also suggested from earlier studies that the analgesia evoked from the lPAG accompanying these active coping responses are somatotopic in nature (Fardin et al., 1984; Nichols and Thorn, 1990). That is, the analgesia is specific to the area of the body from which the noxious inputs originate.
5.16 - Descending Control Mechanisms
2020, The Senses: A Comprehensive Reference: Volume 1-7, Second EditionMicrocircuit Mechanisms through which Mediodorsal Thalamic Input to Anterior Cingulate Cortex Exacerbates Pain-Related Aversion
2019, NeuronCitation Excerpt :We still do not understand the downstream mechanism(s) through which SC neuron inhibition elicits pain-related aversion, but at least two possibilities should be considered. One arises from the fact that a population of SC neurons in the ACC likely projects to the PAG, a region strongly implicated in mechanisms of pain relief (Young and Chambi, 1987; Fardin et al., 1984). In the setting of chronic pain, the increased inhibition of SC-PAG projecting neurons could suppress the excitatory drive to the PAG, thereby reducing its antinociceptive actions and exacerbating the aversiveness of a chronic pain state.