Abstract
Objective
To demonstrate feasibility of near-real-time oculodynamic magnetic resonance imaging (od-MRI) in depicting extraocular muscles and correlate quantitatively the motion degree in comparison with clinical testing in patients with diplopia.
Methods
In 30 od-MRIs eye movements were tracked in the horizontal and sagittal plane using a a TrueFISP sequence with high temporal resolution. Three physicians graded the visibility of extraocular muscles by a qualitative scale. In 12 cases, the maximal monocular excursions in the horizontal and vertical direction of both eyes were measured in od-MRIs and a clinical test and correlated by the Pearson test.
Results
The medial and lateral rectus muscles were visible in the axial plane in 93% of the cases. The oblique, superior and inferior rectus muscles were overall only in 14% visible. Horizontal (p = 0,015) and vertical (p = 0,029) movements of the right eye and vertical movement of the left eye (p = 0,026) measured by od-MRI correlated positively to the clinical measurements.
Conclusions
Od-MRI is a feasible technique. Visualization of the horizontal/vertical rectus muscles is better than for the superior/inferior oblique muscle. Od-MRI correlates well with clinical testing and may reproduce the extent of eye bulb motility and extraocular muscle structural or functional deteriorations.
Key Points
• Oculodynamic MRI technique helps clinicians to assess eye bulb motility disorders
• MRI evaluation of eye movement provides functional information in cases of diplopia
• Oculodynamic MRI reproduces excursion of extraocular muscles with good correlation with clinical testing
• Dynamic MRI sequence supplements static orbital protocol for evaluation of motility disorders
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Acknowledgements
Christoph Kunz and Carlos Buitrago-Tellez contributed equally to this work. Special thanks to the MRI radiological technician team of the Department of Radiology of the University of Basel, Switzerland for valuable support for image acquisition
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Berg, I., Palmowski-Wolfe, A., Schwenzer-Zimmerer, K. et al. Near-real time oculodynamic MRI: a feasibility study for evaluation of diplopia in comparison with clinical testing. Eur Radiol 22, 358–363 (2012). https://doi.org/10.1007/s00330-011-2232-1
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DOI: https://doi.org/10.1007/s00330-011-2232-1