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Contralateral cortical projections to the superior colliculus in the macaque monkey

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Summary

Cortical projections from the contralateral hemisphere to the superior colliculus (SC) were studied in macaque monkey using retrograde transport of the enzyme horseradish peroxidase (HRP). After single or multiple injections of HRP into SC, labelled cells were found contralaterally in layer V of the anterior bank of the arcuate sulcus, the origin of this contralateral projection being confined to the anterior part of Brodmann's area 6. Only a few labelled cells appeared in adjacent area 8. Labelled cells occured in patches, forming bands which were found to run in a ventromedial direction. A similar pattern was seen homotopically in ipsilateral area 6. Thus, this anterior part of area 6 gives rise to a bilateral projection to the SC. The findings emphasize structural differences in a region of the frontal lobe which has been considered functionally uniform as frontal eye field.

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References

  • Adams JC (1980) Stabilizing and rapid staining of TMB based HRP reaction product. Neurosci Lett 17: 7–9

    Google Scholar 

  • Baleydier C (1977) A bilateral cortical projection to the superior colliculus in the cat. Neurosci Lett 4: 9–14

    Google Scholar 

  • Brodmann K (1905) Beiträge zur histologischen Lokalisation der Großhirnrinde. J Psychol Neurol (Lpz) 4: 176–226

    Google Scholar 

  • Catsman-Berrevoets CE, Kuypers HGJM, Lemon RN (1979) Cells of origin of frontal projections to magnocellular and parvocellular red nucleus and superior colliculus in cynomolgus monkey. An HRP study. Neurosci Lett 12: 41–46

    Google Scholar 

  • Distel H, Fries W (1981) Sources of subcortical projections to the superior colliculus in the monkey. Invest Ophthalmol Vis Sci [Suppl] 20: 74

    Google Scholar 

  • Fries W, Distel H (1981) Cortical projections to the superior colliculus in the monkey: A retrograde study using horseradish peroxidase. Invest Ophthalmol Vis Sci [Suppl] 20: 74

    Google Scholar 

  • Illing RB, Wässle H (1979) Visualization of the HRP reaction product using the polarization microscope. Neurosci Lett 13: 7–11

    Google Scholar 

  • Latto R, Cowey A (1971) Visual field defects after frontal eye-field lesions in monkeys. Brain Res 30: 1–24

    Article  CAS  PubMed  Google Scholar 

  • Leichnetz GR, Spencer RF, Hardy SGP, Astruc J (1981) The prefrontal corticotectal projection in the monkey; an anterograde and retrograde study. Neurosci 6: 1023–1041

    Google Scholar 

  • Malmgren L, Olsson Y (1978) A sensitive method for histochemical demonstration of horseradish peroxidase in neurons following retrograde axonal transport. Brain Res 148: 279–294

    Google Scholar 

  • Mesulam MM (1978) Tetramethylbenzidine for horseradish peroxidase neurohistochemistry: A non-carcinogenic blue reaction product with superior sensitivity for visualizing neural afferents and efferents. J Histochem Cytochem 26: 106–117

    CAS  PubMed  Google Scholar 

  • Payne BR, Berman N (1981) The origin of the crossed cortico-collicular projection in the cat. Soc Neurosci Abstr 7: 760

    Google Scholar 

  • Paula-Barbosa MM, Sousa-Pinto A (1973) Auditory projections to the superior colliculus in the cat. Brain Res 50: 47–61

    Google Scholar 

  • Powell TPS (1976) Bilateral cortico-tectal projection from the visual cortex in the cat. Nature 260: 526–527

    Google Scholar 

  • Robinson DA, Fuchs AF (1969) Eye movements evoked by stimulation of the frontal eye field. J Neurophysiol 32: 637–648

    Google Scholar 

  • Schiller PH, True SD, Conway JL (1980) Deficits in eye movements following frontal eye-field and superior colliculus ablations. J Neurophysiol 44: 1175–1189

    CAS  PubMed  Google Scholar 

  • Sprague JM, Meikle TH (1965) The role of the superior colliculus in visually guided behavior. Exp Neurol 11: 115–146

    Google Scholar 

  • Sprague JM, Berlucchi G, Rizzolatti G (1973) The role of the superior colliculus and pretectum in vision and visually guided behavior. In: Jung R (ed) Handbook of sensory physiology, vol VII/3B. Springer, Berlin Heidelberg New York, pp 27–101

    Google Scholar 

  • Tortelli A, Reinoso-Suarez F, Llamas A (1980) Projections from non-visual cortical areas to the superior colliculus demonstrated by retrograde transport of HRP in the cat. Brain Res 188: 543–549

    Google Scholar 

  • Wurtz RH, Albano JE (1980) Visual motor function of the primate superior colliculus. Ann Rev Neurosci 3: 189–226

    Google Scholar 

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Authors and Affiliations

  1. Institut für Medizinische Psychologie, Ludwig-Maximilians-Universität München, Schillerstr. 42, D-8000, München 2, Germany

    H. Distel & W. Fries

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  1. H. Distel
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  2. W. Fries
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Supported by Deutsche Forschungsgemeinschaft (SFB 50/C6 and Di 212/2)

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Distel, H., Fries, W. Contralateral cortical projections to the superior colliculus in the macaque monkey. Exp Brain Res 48, 157–162 (1982). https://doi.org/10.1007/BF00237210

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  • DOI: https://doi.org/10.1007/BF00237210

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