FMRI Visualization of Brain Activity during a Monetary Incentive Delay Task

doi:10.1006/nimg.2000.0593

NeuroImage

Volume 12, Issue 1, July 2000, Pages 20-27

https://doi.org/10.1006/nimg.2000.0593 Get rights and content

Abstract

Comparative studies have implicated striatal and mesial forebrain circuitry in the generation of autonomic, endocrine, and behavioral responses for incentives. Using blood oxygen level-dependent functional magnetic resonance imaging, we sought to visualize functional activation of these regions in 12 normal volunteers as they anticipated and responded for monetary incentives. Both individual and group analyses of time-series data revealed significant activation of striatal and mesial forebrain structures (including insula, caudate, putamen, and mesial prefrontal cortex) during trials involving both monetary rewards and punishments. In addition to these areas, during trials involving punishment, group analysis revealed activation foci in the anterior cingulate and thalamus. These results corroborate comparative studies which implicate striatal and mesial forebrain circuitry in the elaboration of incentive-driven behavior. This report also introduces a new paradigm for probing the functional integrity of this circuitry in humans.

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Regular ArticleFMRI Visualization of Brain Activity during a Monetary Incentive Delay Task

Abstract

NeuroImage

Neuron

Magn. Reson. Imag.

Comput. Biomed. Res.

Trends Cognit. Sci.

Brain Res. Rev.

Neuron

Behav. Brain Res.

Neuropharmacology

Neurosci. Res.

Prefrontal cortical projections to longitudinal columns in the midbrain periqueductal gray in macaque monkeys

J. Comp. Neurol.

An FMRI version of the Farnsworth–Munsell 100-Hue Test reveals multiple color-selective areas in human ventral occipitotemporal cortex

Cereb. Cortex

Amygdala–hippocampal involvement in human aversive trace conditioning revealed through event-related functional magnetic resonance imaging

J. Neurosci.

Event-related FMRI and the hemodynamic response

Hum. Brain Mapp.

Role of the cerebral cortex in autonomic function

Functional neuroanatomical correlates of electrodermal activity: A positron emission tomographic study

Psychophysiology

Functional organization of human supplementary motor cortex studied by electrical stimulation

J. Neurosci.

Evoked extracellular dopamine in vivo in the medial prefrontal cortex

J. Neurochem.

Regular Article
FMRI Visualization of Brain Activity during a Monetary Incentive Delay Task