Regular ArticleReduced Size of Retinal Ganglion Cell Axons and Hypomyelination in Mice Lacking Brain-Derived Neurotrophic Factor☆
References (57)
- et al.
Localization of cellular storage compartments and sites of constitutive and activity-dependent release of nerve growth factor (NGF) in primary cultures of hippocampal neurons
Mol. Cell. Neurosci.
(1996) - et al.
Synaptic innervation density is regulated by neuron-derive BDNF
Neuron
(1997) - et al.
Single-step method of RNA isolation by guanidium thiocyanate–phenol–chloroform extraction
Anal. Biochem.
(1987) - et al.
BDNF in the development of the visual system of Xenopus
Neuron
(1994) - et al.
Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development
Cell
(1994) - et al.
Neurotrophins and their receptors in the rat pituitary gland: Regulation of BDNF and trkB mRNA levels by adrenal hormones
Mol. Brain Res.
(1994) - et al.
Intravitreal injections of neurotrophic factors support the survival of axotomized retinal ganglion cells in adult rats in vivo
Brain Res.
(1993) - et al.
Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells
Neuron
(1995) Neurotrophic survival molecules for motoneurons: An embarrassment of riches
Neuron
(1996)- et al.
Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice
Neuron
(1996)
Expression of Brain-Derived Neurotrophic Factor and its functional receptor in neonatal and adult rat retina
Neurosci. Lett.
The survival of chick retinal ganglion cells in response to brain-derived neurotrophic factor depends on their embryonic age
Dev. Biol.
Functions of the neurotrophins during nervous system development: What the knock-out are teaching us
Cell
Positive and negative effects of neurotrophins on the isthmo-optic nucleus in chick embryos
Neuron
TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons form axotomy-induced cell death
J. Neurosci.
A crucial role for neurotrophin-3 in oligodendrocyte development
Nature
A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development
Development
Proliferation of oligodendrocyte precursor cells depends on electrical activity in axons
Nature
Neurotrophin-3 antibodies disrupt the normal development of the chick retina
J. Neurosci.
Glial cells are increased proportionally in transgenic optic nerves with increased number of axons
J. Neurosci.
Role of target tissue in regulating the development of retinal ganglion cells in the albino rat: Effects of kainate lesions in the superior colliculus
J. Comp. Neurol.
Brain derived neurotrophic factor and the developing chick retina
Life and Death in the Nervous System
Neurological consequences of protein and protein-calorie undernutrition
Crit. Rev. Neurobiol.
Nerve growth factor and neurotrophin-3 differentially regulate the proliferation and survival of developing rat brain oligodendrocytes
J. Neurosci.
Effects of brain-derived neurotrophic factor on optic axon branching and remodellingin vivo
Nature
Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: Evidence for anterograde axonal transport
J. Neurosci.
Neuronal deficits, not involving motor neurons, in mice lacking BDNF and/or NT-4
Nature
At least two mechanisms are involved in the death of retinal ganglion cells following target ablation in neonatal rats
J. Neurosci.
Cited by (177)
Evaluation of BCAS1-positive immature oligodendrocytes after cerebral ischemic stroke and SVD
2023, Neuroscience LettersBDNF haploinsufficiency exerts a transient and regionally different influence upon oligodendroglial lineage cells during postnatal development
2018, Molecular and Cellular NeuroscienceCitation Excerpt :Previous studies have revealed that BDNF plays an important role in glial cell functions such as myelination. Analysis of BDNF knockout (KO) mice has revealed significantly reduced expression of myelin marker protein MBP in all brain areas including the hippocampus (Djalali et al., 2005), significant reductions in the expression of mRNAs coding for MBP and proteolipid protein (PLP) in both the hippocampus and the cortex (Djalali et al., 2005), and significantly fewer myelinated axons in the optic nerve (Cellerino et al., 1997). However due to their failure to thrive, poor health and early postnatal lethality, BDNF KO mice have limited utility for detailed examination of myelin development (Cellerino et al., 1997; Djalali et al., 2005).
The Initial Myelination in the Central Nervous System
2023, ASN Neuro
- ☆
C. F. Ibanez, Ed.
- 1
To whom correspondence should be addressed at present address: Department of Neuroophthalmology, University Eye Hospital, Roentgen Weg 11, D-72076 Tübingen, Germany. Fax: (+49)-7071-295777. E-mail: [email protected].
- 2
Present address: INSERM U 382, IBDM, Marseilles, France.