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α-synuclein

  • α-Synuclein Aggregates Increase the Conductance of Substantia Nigra Dopamine Neurons, an Effect Partly Reversed by the KATP Channel Inhibitor Glibenclamide
    Research ArticleResearch Article: New Research, Disorders of the Nervous System
    α-Synuclein Aggregates Increase the Conductance of Substantia Nigra Dopamine Neurons, an Effect Partly Reversed by the KATP Channel Inhibitor Glibenclamide
    E. Hill, R. Gowers, M. J. E. Richardson and M. J. Wall
    eNeuro 23 November 2020, 8 (1) ENEURO.0330-20.2020; DOI: https://doi.org/10.1523/ENEURO.0330-20.2020
  • The SUMO Conjugase Ubc9 Protects Dopaminergic Cells from Cytotoxicity and Enhances the Stability of α-Synuclein in Parkinson’s Disease Models
    Research ArticleResearch Article: New Research, Disorders of the Nervous System
    The SUMO Conjugase Ubc9 Protects Dopaminergic Cells from Cytotoxicity and Enhances the Stability of α-Synuclein in Parkinson’s Disease Models
    Dinesh Kumar Verma, Anurupa Ghosh, Lindsey Ruggiero, Etienne Cartier, Eric Janezic, Dionne Williams, Eui-Gil Jung, Michael Moore, Jong Bok Seo and Yong-Hwan Kim
    eNeuro 4 September 2020, 7 (5) ENEURO.0134-20.2020; DOI: https://doi.org/10.1523/ENEURO.0134-20.2020
  • Developmental Changes in Dendritic Spine Morphology in the Striatum and Their Alteration in an A53T α-Synuclein Transgenic Mouse Model of Parkinson’s Disease
    Research ArticleResearch Article: New Research, Disorders of the Nervous System
    Developmental Changes in Dendritic Spine Morphology in the Striatum and Their Alteration in an A53T α-Synuclein Transgenic Mouse Model of Parkinson’s Disease
    Laxmi Kumar Parajuli, Ken Wako, Suiki Maruo, Soichiro Kakuta, Tomoyuki Taguchi, Masashi Ikuno, Hodaka Yamakado, Ryosuke Takahashi and Masato Koike
    eNeuro 17 August 2020, 7 (4) ENEURO.0072-20.2020; DOI: https://doi.org/10.1523/ENEURO.0072-20.2020
  • <em>Snca</em>-GFP Knock-In Mice Reflect Patterns of Endogenous Expression and Pathological Seeding
    Research ArticleResearch Article: Methods/New Tools, Disorders of the Nervous System
    Snca-GFP Knock-In Mice Reflect Patterns of Endogenous Expression and Pathological Seeding
    Anna Caputo, Yuling Liang, Tobias D. Raabe, Angela Lo, Mian Horvath, Bin Zhang, Hannah J. Brown, Anna Stieber and Kelvin C. Luk
    eNeuro 11 August 2020, 7 (4) ENEURO.0007-20.2020; DOI: https://doi.org/10.1523/ENEURO.0007-20.2020
  • Chronic α-Synuclein Accumulation in Rat Hippocampus Induces Lewy Bodies Formation and Specific Cognitive Impairments
    Research ArticleResearch Article: New Research, Disorders of the Nervous System
    Chronic α-Synuclein Accumulation in Rat Hippocampus Induces Lewy Bodies Formation and Specific Cognitive Impairments
    Danielle Walu Kasongo, Gioacchino de Leo, Nunzio Vicario, Giampiero Leanza and Giuseppe Legname
    eNeuro 11 May 2020, 7 (3) ENEURO.0009-20.2020; DOI: https://doi.org/10.1523/ENEURO.0009-20.2020
  • Long-Term Exposure to PFE-360 in the AAV-α-Synuclein Rat Model: Findings and Implications
    Research ArticleNew Research, Disorders of the Nervous System
    Long-Term Exposure to PFE-360 in the AAV-α-Synuclein Rat Model: Findings and Implications
    Michael Aagaard Andersen, Florence Sotty, Poul Henning Jensen, Lassina Badolo, Ross Jeggo, Garrick Paul Smith and Kenneth Vielsted Christensen
    eNeuro 4 November 2019, 6 (6) ENEURO.0453-18.2019; DOI: https://doi.org/10.1523/ENEURO.0453-18.2019
  • α-Synuclein-Dependent Calcium Entry Underlies Differential Sensitivity of Cultured SN and VTA Dopaminergic Neurons to a Parkinsonian Neurotoxin
    Research ArticleNew Research, Disorders of the Nervous System
    α-Synuclein-Dependent Calcium Entry Underlies Differential Sensitivity of Cultured SN and VTA Dopaminergic Neurons to a Parkinsonian Neurotoxin
    Ori J. Lieberman, Se Joon Choi, Ellen Kanter, Anastasia Saverchenko, Micah D. Frier, Giulia M. Fiore, Min Wu, Jyothisri Kondapalli, Enrico Zampese, D. James Surmeier, David Sulzer and Eugene V. Mosharov
    eNeuro 15 November 2017, 4 (6) ENEURO.0167-17.2017; DOI: https://doi.org/10.1523/ENEURO.0167-17.2017
  • Overexpression of Parkinson’s Disease-Associated Mutation LRRK2 G2019S in Mouse Forebrain Induces Behavioral Deficits and α-Synuclein Pathology
    Research ArticleNew Research, Disorders of the Nervous System
    Overexpression of Parkinson’s Disease-Associated Mutation LRRK2 G2019S in Mouse Forebrain Induces Behavioral Deficits and α-Synuclein Pathology
    Yulan Xiong, Stewart Neifert, Senthilkumar S. Karuppagounder, Jeannette N. Stankowski, Byoung Dae Lee, Jonathan C. Grima, Guanxing Chen, Han Seok Ko, Yunjong Lee, Debbie Swing, Lino Tessarollo, Ted M. Dawson and Valina L. Dawson
    eNeuro 6 March 2017, 4 (2) ENEURO.0004-17.2017; DOI: https://doi.org/10.1523/ENEURO.0004-17.2017
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