Table 1.

Equations and parameters for the single-compartment WB model

VariableEquation
Membrane potential V Embedded Image
Leak current Embedded Image
Delayed rectifier K current Embedded Image
Fast (transient) Na current Embedded Image
Intracellularly injected current Embedded Image (default)
Kinetic equations for channel variables
(y = m, h, or n)
Embedded Image
Rate functions for K activation n Embedded Image
Embedded Image
Rate functions for Na activation m Embedded Image
Embedded Image
Rate functions for Na inactivation h Embedded Image
Embedded Image
ParameterValue
Membrane capacitance density Cm1.0 μF/cm2
Leak conductance density GL0.1 mS/cm2
K conductance density GK15.0 mS/cm2
Na conductance density GNa35.0 mS/cm2
Leak reversal potential EL-65 mV
K reversal potential EK-90 mV
Na reversal potential ENa+55 mV