WT (N) | KO (N) | |
---|---|---|
Long-term studies | ||
SCI | 21 | 24 |
BMS | 21 | 24 |
Grid-walk | 13 | 8 |
White matter sparing | 11 | 8 |
Acute studies | ||
Uninjured | 7 | 7 |
SCI | 19 | 19 |
Immunoblotting | 8 | 8 |
Flow cytometry | 18 | 18 |
Vehicle (N) | Diclofenac (N) | |
Long-term studies | ||
SCI (WT) | 75 | 122 |
SCI (KO) | 6 | 5 |
BMS | 79 | 109 |
Grid walk | 4 | 11 |
White matter sparing | 14 | 28 |
Mortality (single dose) | 2 | 1 |
Mortality (two doses) | N/A | 8 |
Mortality (three doses) | N/A | 9 |
Acute studies | ||
In vitro | 21 (pooled) | |
Uninjured | 18 | 18 |
SCI | 29 | 107 |
Flow cytometry | 25 | 25 |
ELISA | 17 | 95 |
Immunoblotting | 5 | 5 |