Summary of statistics.
Table analyzed | Statistical test | p value | Size effect | t value | df | R2 | F value | |
---|---|---|---|---|---|---|---|---|
WT vs KO | BrdU counts | Unpaired Student’s t test | 0.8469 | 0.60 | 0.494 | 8 | 0.029 | 9.72 p = 0.049 |
BrdU-Prox1 colocalization | Unpaired Student’s t test | 0.6784 | 0.23 | 0.3652 | 8 | 0.016 | 5.473 p = 0.1284 | |
% Newborn neurons | Unpaired Student’s t test | 0.2214 | 0.19 | 0.2983 | 8 | 0.011 | 1.266 p = 0.8249 | |
Nestin-Ki67-GFAP | Unpaired Student’s t test | 0.0376 | 1.88 | 2.658 | 6 | 0.5408 | 8.054 p = 0.1204 | |
Nestin-GFAP | Unpaired Student’s t test | .0291 | 2.02 | 2.851 | 6 | 0.575 | 1.639 p = 0.6947 | |
Ki67 | Unpaired Student’s t test | 0.0333 | 2.47 | 2.75 | 6 | 0.5576 | 1.015 p = 0.9903 | |
Length of the first branch | Unpaired Student’s t test | 0.1658 | 0.23 | 1.393 | 149 | 0.0128 | 1.284 p = 0.2817 | |
Number of nodes | Unpaired Student’s t test | 0.0001 | 0.65 | 3.939 | 149 | 0.0943 | 1.617 p = 0.0406 | |
DA cumulative length | Unpaired Student’s t test | 0.1117 | 0.26 | 1.6 | 149 | 0.0169 | 1.133 p = 0.5929 | |
DA span | Unpaired Student’s t test | 0.0032 | 0.49 | 2.967 | 149 | 0.05578 | 3.387 p = 0.0001 | |
Sholl analysis | ||||||||
Intersection effect | Two-way ANOVA | <0.0001 | F(26,4023) = 2.488 | |||||
Row effect | Two-way ANOVA | <0.0001 | F(26,4023) = 163.7 | |||||
Column effect | Two-way ANOVA | <0.0001 | F(1,4023) = 37.46 | |||||
Spine density | Unpaired Student’s t test | <0.0001 | 1.13 | 4.163 | 107 | 0.1394 | 1.016 p = 0.9479 | |
E3 vs E4 | BrdU Counts | Unpaired Student’s t test | 0.8961 | 0.094 | 0.135 | 7 | 0.002612 | 2.668 p = 0.4463 |
BrdU-Prox1 colocalization | Unpaired Student’s t test | 0.5838 | 0.40 | 0.574 | 7 | 0.04498 | 3.759 p = 0.3053 | |
% Newborn neurons | Unpaired Student’s t test | 0.1097 | 1.22 | 1.832 | 7 | 0.324 | 1.234 p = 0.8143 | |
Nestin-Ki67-GFAP | Unpaired Student’s t test | 0.486 | 0.52 | 0.7419 | 6 | 0.6185 | 1.875 p = 0.6185 | |
Nestin-GFAP | Unpaired Student’s t test | 0.3700 | 0.69 | 0.9689 | 6 | 0.1351 | 1.191 p = 0.8891 | |
Ki67 | Unpaired Student’s t test | 0.2795 | 0.84 | 1.189 | 6 | 0.1906 | 2.6 p = 0.4533 | |
Length of the first branch | Unpaired Student’s t test | 0.8949 | 0.023 | 0.132 | 142 | 0.000123 | 1.09 p = 0.7196 | |
Number of nodes | Unpaired Student’s t test | 0.0007 | 0.59 | 3.472 | 142 | 0.07826 | 1.408, p = 0.1542 | |
DA cumulative length | Unpaired Student’s t test | <0.0001 | 0.7 | 4.127 | 142 | 0.1071 | 1.783, p = 0.0166 | |
DA Span | Unpaired Student’s t test | 0.5978 | 0.09 | 0.528 | 142 | 0.001965 | 1.296, p = 0.2749 | |
Sholl analysis | ||||||||
Intersection effect | Two-way ANOVA | 0.0013 | F(26,3834) = 2.048 | |||||
Row effect | Two-way ANOVA | <0.0001 | F(26,3834) = 144.7 | |||||
Column effect | Two-way ANOVA | <0.0001 | F(1,3834) = 112.8 | |||||
Spine density | Unpaired Student’s t test | <0.0001 | 1.13 | 5.278 | 88 | 0.2405 | 2.08 p = 0.0173 |
D, Dendritic arborization. Cohen’s d value was calculated as
with
, d = 0.2, d = 0.5, and d = 0.8 corresponding to small, medium, and large size effects, respectively