Regions showing significant bilateral group × session interactions for clustering coefficient
Regions | Baseline | 1d Abs | 14d Abs | ||||||
---|---|---|---|---|---|---|---|---|---|
Chamber control | Sucrose SA | Cocaine SA | Chamber control | Sucrose SA | Cocaine SA | Chamber control | Sucrose SA | Cocaine SA | |
CeA | 0.27 ± 0.02 | 0.33 ± 0.06 | 0.35 ± 0.02 | 0.29 ± 0.03 | 0.47 ± 0.06 | 0.43 ± 0.04* | 0.41 ± 0.05 | 0.31 ± 0.02 | 0.39 ± 0.06 |
BaA | 0.28 ± 0.02 | 0.35 ± 0.04 | 0.35 ± 0.03 | 0.28 ± 0.03 | 0.41 ± 0.05 | 0.41 ± 0.05* | 0.36 ± 0.04 | 0.30 ± 0.01 | 0.31 ± 0.04 |
NAc | 0.25 ± 0.04 | 0.33 ± 0.06 | 0.30 ± 0.03 | 0.31 ± 0.05 | 0.42 ± 0.05 | 0.49 ± 0.08* | 0.41 ± 0.06 | 0.28 ± 0.03 | 0.33 ± 0.03 |
dHPC | 0.32 ± 0.04 | 0.42 ± 0.07 | 0.34 ± 0.04 | 0.32 ± 0.05 | 0.45 ± 0.11 | 0.46 ± 0.03* | 0.41 ± 0.03 | 0.38 ± 0.04 | 0.31 ± 0.02 |
VP | 0.28 ± 0.02 | 0.34 ± 0.05 | 0.36 ± 0.05 | 0.30 ± 0.06 | 0.43 ± 0.04 | 0.50 ± 0.08* | 0.42 ± 0.04 | 0.31 ± 0.02 | 0.35 ± 0.04 |
GP | 0.28 ± 0.03 | 0.31 ± 0.04 | 0.37 ± 0.04 | 0.34 ± 0.05 | 0.43 ± 0.01 | 0.47 ± 0.07 | 0.39 ± 0.05 | 0.27 ± 0.03 | 0.30 ± 0.05 |
LH | 0.28 ± 0.02 | 0.34 ± 0.03 | 0.40 ± 0.03 | 0.30 ± 0.02 | 0.39 ± 0.05 | 0.45 ± 0.05* | 0.35 ± 0.04 | 0.31 ± 0.03 | 0.32 ± 0.04 |
PV Thal | 0.31 ± 0.02 | 0.41 ± 0.05 | 0.39 ± 0.05 | 0.34 ± 0.05 | 0.51 ± 0.04 | 0.55 ± 0.07* | 0.42 ± 0.04 | 0.30 ± 0.02 | 0.34 ± 0.05 |
AP Thal | 0.31 ± 0.01 | 0.45 ± 0.06 | 0.40 ± 0.04 | 0.32 ± 0.04 | 0.46 ± 0.08 | 0.58 ± 0.06* | 0.40 ± 0.03 | 0.30 ± 0.04 | 0.33 ± 0.03 |
RN Thal | 0.29 ± 0.04 | 0.33 ± 0.07 | 0.39 ± 0.04 | 0.32 ± 0.05 | 0.43 ± 0.05 | 0.41 ± 0.04 | 0.45 ± 0.06 | 0.28 ± 0.04 | 0.34 ± 0.05 |
MD Thal | 0.35 ± 0.03 | 0.42 ± 0.04 | 0.33 ± 0.03 | 0.32 ± 0.05 | 0.41 ± 0.05 | 0.48 ± 0.06* | 0.36 ± 0.03 | 0.32 ± 0.02 | 0.30 ± 0.02 |
VL Thal | 0.32 ± 0.02 | 0.35 ± 0.03 | 0.38 ± 0.03 | 0.32 ± 0.04 | 0.45 ± 0.04* | 0.47 ± 0.05* | 0.40 ± 0.03 | 0.30 ± 0.00 | 0.38 ± 0.01 |
VPM Thal | 0.27 ± 0.04 | 0.35 ± 0.06 | 0.35 ± 0.03 | 0.32 ± 0.03 | 0.57 ± 0.06* | 0.39 ± 0.08* | 0.38 ± 0.05 | 0.32 ± 0.03 | 0.34 ± 0.04 |
LP Thal | 0.33 ± 0.02 | 0.41 ± 0.08 | 0.35 ± 0.04 | 0.31 ± 0.03 | 0.47 ± 0.10* | 0.54 ± 0.04* | 0.37 ± 0.03 | 0.26 ± 0.04 | 0.31 ± 0.02 |
Pf Thal | 0.30 ± 0.03 | 0.39 ± 0.05 | 0.31 ± 0.03 | 0.29 ± 0.04 | 0.46 ± 0.01* | 0.51 ± 0.06* | 0.42 ± 0.07 | 0.32 ± 0.01 | 0.34 ± 0.02 |
LG Thal | 0.33 ± 0.03 | 0.41 ± 0.04 | 0.33 ± 0.05 | 0.33 ± 0.05 | 0.47 ± 0.04 | 0.52 ± 0.04* | 0.40 ± 0.06 | 0.33 ± 0.03 | 0.37 ± 0.04 |
PrL | 0.33 ± 0.02 | 0.36 ± 0.05 | 0.30 ± 0.02 | 0.31 ± 0.05 | 0.41 ± 0.02 | 0.40 ± 0.03 | 0.43 ± 0.06 | 0.31 ± 0.02 | 0.36 ± 0.04 |
IL | 0.30 ± 0.03 | 0.28 ± 0.02 | 0.30 ± 0.01 | 0.31 ± 0.06 | 0.49 ± 0.12 | 0.43 ± 0.06 | 0.43 ± 0.08 | 0.28 ± 0.03 | 0.32 ± 0.04 |
M2 | 0.29 ± 0.03 | 0.28 ± 0.00 | 0.39 ± 0.05 | 0.29 ± 0.05 | 0.33 ± 0.07 | 0.46 ± 0.06 | 0.50 ± 0.08 | 0.31 ± 0.03 | 0.36 ± 0.03 |
S1 jw | 0.29 ± 0.03 | 0.39 ± 0.04 | 0.28 ± 0.02 | 0.31 ± 0.04 | 0.42 ± 0.04 | 0.38 ± 0.08 | 0.43 ± 0.04 | 0.30 ± 0.03 | 0.34 ± 0.05 |
S1 ul | 0.28 ± 0.02 | 0.31 ± 0.01 | 0.37 ± 0.05 | 0.29 ± 0.03 | 0.38 ± 0.05 | 0.44 ± 0.07* | 0.40 ± 0.03 | 0.30 ± 0.04 | 0.35 ± 0.04 |
S1 Sh | 0.29 ± 0.02 | 0.36 ± 0.03 | 0.33 ± 0.03 | 0.33 ± 0.05 | 0.44 ± 0.05 | 0.49 ± 0.07* | 0.38 ± 0.04 | 0.29 ± 0.02 | 0.32 ± 0.04 |
S2 | 0.28 ± 0.03 | 0.33 ± 0.02 | 0.39 ± 0.05 | 0.31 ± 0.05 | 0.39 ± 0.06 | 0.48 ± 0.05* | 0.40 ± 0.03 | 0.26 ± 0.04 | 0.33 ± 0.06 |
Data are shown as the mean ± SEM for sucrose or cocaine SA rats and chamber exposure controls at baseline, 1d Abs, and 14d Abs. CeA, Central amygdala; BaA, basal amygdala; dHPC, dorsal hippocampus; VP, ventral pallidum; GP, globus pallidus; LH, lateral hypothalamus; Thal, thalamus; PV, paraventricular; AP, anteroposterior; RN, reticular nucleus; MD, mediodorsal; VL, ventrolateral; VPM, ventroposteromedial; LP, lateroposterior; Pf, parafascicular; LG, lateral genticulate; PrL, prelimbic; IL, infralimbic; M2, secondary motor; S1, primary somatosensory cortex; jw, jaw region, ul, upper lip; Sh, shoulder; S2, secondary somatosensory cortex. All regions in the table showed significant group × session interactions with a repeated-measures two-factor ANOVA (α < 0.05).
Asterisks represent the results of Tukey’s multiple-comparison post hoc test: *difference from chamber exposure controls; **difference between cocaine and sucrose groups.