Table 2.

Regions showing significant lateralized group × session interactions for clustering coefficient

RegionsBaseline1d Abs14d Abs
Chamber controlSucrose SACocaine SAChamber controlSucrose SACocaine SAChamber controlSucrose SACocaine SA
LaA (R)0.29 ± 0.030.32 ± 0.040.30 ± 0.040.30 ± 0.020.40 ± 0.060.47 ± 0.06*0.40 ± 0.050.33 ± 0.020.34 ± 0.03
MeA (R)0.31 ± 0.030.38 ± 0.060.41 ± 0.020.32 ± 0.030.43 ± 0.040.49 ± 0.06*0.41 ± 0.060.27 ± 0.020.32 ± 0.04
DMS (L)0.30 ± 0.040.29 ± 0.050.39 ± 0.050.31 ± 0.050.46 ± 0.040.49 ± 0.05*0.44 ± 0.040.28 ± 0.020.37 ± 0.04
LSept (R)0.30 ± 0.020.29 ± 0.030.39 ± 0.040.35 ± 0.080.37 ± 0.090.56 ± 0.07*0.42 ± 0.040.26 ± 0.010.32 ± 0.04
AHA (R)0.28 ± 0.030.35 ± 0.030.34 ± 0.030.30 ± 0.030.49 ± 0.04*0.51 ± 0.07*0.41 ± 0.060.34 ± 0.050.36 ± 0.05
MB (R)0.28 ± 0.030.37 ± 0.050.32 ± 0.020.31 ± 0.030.41 ± 0.090.51 ± 0.09*0.42 ± 0.050.32 ± 0.020.36 ± 0.04
VM Thal (R)0.34 ± 0.030.43 ± 0.040.40 ± 0.030.31 ± 0.030.51 ± 0.05*0.52 ± 0.07*0.40 ± 0.060.28 ± 0.040.36 ± 0.03
PThal (R)0.34 ± 0.030.36 ± 0.070.38 ± 0.030.32 ± 0.030.45 ± 0.080.47 ± 0.04*0.35 ± 0.030.29 ± 0.020.33 ± 0.03
MG Thal (L)0.31 ± 0.020.38 ± 0.040.41 ± 0.040.36 ± 0.070.45 ± 0.050.52 ± 0.050.45 ± 0.090.38 ± 0.040.35 ± 0.04
cRSC (L)0.39 ± 0.040.34 ± 0.030.35 ± 0.050.38 ± 0.050.60 ± 0.07*0.51 ± 0.050.46 ± 0.040.36 ± 0.050.36 ± 0.02
M1 (L)0.26 ± 0.020.29 ± 0.020.29 ± 0.030.31 ± 0.040.40 ± 0.070.38 ± 0.050.45 ± 0.050.32 ± 0.020.33 ± 0.04
S1 Tr (R)0.31 ± 0.030.44 ± 0.090.40 ± 0.060.26 ± 0.040.43 ± 0.070.48 ± 0.06*0.48 ± 0.090.38 ± 0.030.32 ± 0.02
PRhC (L)0.30 ± 0.020.27 ± 0.040.30 ± 0.030.34 ± 0.020.60 ± 0.10*0.41 ± 0.04**0.39 ± 0.050.28 ± 0.020.36 ± 0.04
MRN (L)0.35 ± 0.030.35 ± 0.050.38 ± 0.040.37 ± 0.040.44 ± 0.030.53 ± 0.04*0.38 ± 0.030.43 ± 0.030.34 ± 0.03
Cer2 (L)0.38 ± 0.040.39 ± 0.040.33 ± 0.020.33 ± 0.050.49 ± 0.02*0.46 ± 0.05*0.51 ± 0.050.32 ± 0.02*0.35 ± 0.03*

  • Data are shown as the mean ± SEM for sucrose or cocaine SA rats and chamber exposure controls at baseline, 1d Abs, and 14d Abs. R, Right; L, left; LaA, lateral amygdala; MeA, medial amygdala; DMS, dorsomedial striatum; LSept, lateral septum; AHA, anterior hypothalamic area; MB, mammillary bodies; Thal, thalamus; VM, ventromedial; Pthal, posterior thalamus; MG, medial genticulate; cRSC, caudal retrosplenial cortex; M1, primary motor cortex; S1, primary somatosensory cortex; Tr, trunk region; PRhC, perirhinal cortex; MRN, midbrain reticular nucleus; Cer2, 2nd cerebellar lobule. All regions in table showed significant group x session interactions with a repeated-measures two factor ANOVA (α < 0.05).

  • Asterisks represent results of Tukey’s multiple-comparison post hoc test: *difference from chamber exposure controls; **difference between cocaine and sucrose groups..