Variable | Comparison | Data structure | Statistical test | Output | p value | Post hoc power | Effect size | |
---|---|---|---|---|---|---|---|---|
Percent response trials | kkk | ACUTE Rescue, drug × filament interaction | Non-normal | One-way rmANOVA | F(6.158,351.02) = 2.619 | p = 0.002 | 0.981 | 0.303 |
lll | 0.04 g filament, drug | Non-normal | Simple main effect | F(2,456) = 4.543 | p = 0.011 | 0.772 | 0.139 | |
lll | 0.07 g filament, drug | Non-normal | Simple main effect | F(2,456) = 16.661 | p < 0.000005 | 1 | 0.270 | |
lll | 0.16 g filament, drug | Non-normal | Simple main effect | F(2,456) = 11.590 | p = 0.00001 | 0.994 | 0.225 | |
lll | 0.4 g filament, drug | Non-normal | Simple main effect | F(2,456) = 8.016 | p = 0.0004 | 0.956 | 0.185 | |
lll | 0.6 g filament, drug | Non-normal | Simple main effect | F(2,456) = 7.286 | p = 0.0008 | 0.936 | 0.179 | |
lll | 1.0 g filament, drug | Non-normal | Simple main effect | F(2,456) = 5.487 | p = 0.004 | 0.849 | 0.157 | |
mmm | ACUTE Rescue AUC, drug | Normal | One-way ANOVA | F(2,57) = 15.887 | p < 0.000005 | 0.999 | 0.747 | |
nnn | CHRONIC Rescue, drug × filament interaction | Non-normal | One-way rmANOVA | F(6.665,13.33) = 4.506 | p < 0.000005 | 1 | 0.398 | |
ooo | 0.04 g filament, drug | Non-normal | Simple main effect | F(2,456) = 8.840 | p = 0.0001 | 0.971 | 0.196 | |
ooo | 0.07 g filament, drug | Non-normal | Simple main effect | F(2,456) = 15.357 | p < 0.000005 | 0.999 | 0.259 | |
ooo | 0.16 g filament, drug | Non-normal | Simple main effect | F(2,456) = 21.158 | p < 0.000005 | 1 | 0.305 | |
ooo | 0.4 g filament, drug | Non-normal | Simple main effect | F(2,456) = 16.264 | p < 0.000005 | 1 | 0.266 | |
ooo | 0.6 g filament, drug | Non-normal | Simple main effect | F(2,456) = 15.714 | p < 0.000005 | 0.999 | 0.261 | |
ooo | 1.0 g filament, drug | Non-normal | Simple main effect | F(2,456) = 20.966 | p < 0.000005 | 1 | 0.303 | |
ooo | 1.4 g filament, drug | Non-normal | Simple main effect | F(2,456) = 4.179 | p = 0.016 | 0.735 | 0.135 | |
ppp | CHRONIC Rescue AUC, drug | Normal | One-way ANOVA | F(2,57) = 20.307 | p < 0.000005 | 1 | 0.844 | |
Percent alternating trials | qqq | ACUTE Rescue, drug | Normal | Two-way ANOVA | F(2,54) = 1.766 | p = 0.181 | 0.354 | 0.255 |
rrr | CHRONIC Rescue, drug | Non-normal | Two-way ANOVA | F(2,51) = 0.814 | p = 0.449 | 0.182 | 0.179 | |
Percent tube test bouts won | sss | ACUTE Rescue VEH-VEH, compared to 50% | Non-normal | One-spl Wilcoxon | Z = -5.312 | p < 0.000005 | N/A | 0.74 |
ttt | ACUTE Rescue FLX-VEH, compared to 50% | Non-normal | One-spl Wilcoxon | Z = 2.114 | p = 0.034 | N/A | 0.25 | |
vvv | ACUTE Rescue FLX-FLX, compared to 50% | Non-normal | One-spl Wilcoxon | Z = 4.016 | p = 0.00006 | N/A | 0.85 | |
sss | CHRONIC Rescue VEH-VEH, compared to 50% | Non-normal | One-spl Wilcoxon | Z = -5.533 | p < 0.000005 | N/A | 0.81 | |
uuu | CHRONIC Rescue FLX-VEH, compared to 50% | Non-normal | One-spl Wilcoxon | Z = 1.726 | p = 0.084 | N/A | 0.17 | |
vvv | CHRONIC Rescue FLX-FLX, compared to 50% | Non-normal | One-spl Wilcoxon | Z = 3.934 | p = 0.00008 | N/A | 0.81 | |
Weight | www | ACUTE Rescue, drug | Normal | Two-way ANOVA | F(2,73) = 15.468 | p < 0.000005 | 0.999 | 0.652 |
www | CHRONIC Rescue, drug | Non-normal | Two-way ANOVA | F(2,73) = 18.850 | p < 0.000005 | 1 | 1.814 | |
Distance traveled | xxx | ACUTE Rescue, drug | Normal | Two-way ANOVA | F(2,54) = 2.787 | p = 0.070 | 0.526 | 0.322 |
yyy | CHRONIC Rescue, drug | Normal | Two-way ANOVA | F(2,54) = 7.742 | p = 0.020 | 0.713 | 0.378 |
Effect size for F tests reported as Cohen’s f (Cohen, 1988; interpretation: 0.01 = small; 0.25 = medium; 0.40 = large) and for nonparametric tests reported as η2.