Table 3.

Intrinsic properties of small-diameter DRG neurons from adult WT and TRESK KO mice

Diameter, μmCapacitance, pFRin,MΩVrest, mVRheobase, pAAP threshold, mVAP amplitude, mVAP half-width, msAHP amplitude, mVCell number
Small IB4-negative neurons
    WT21.3 ± 0.522.0 ± 0.9882 ± 135−56.7 ± 1.261 ± 9−15.8 ± 1.7111.9 ± 3.04.7 ± 0.4−18.4 ± 1.516
    KO20.5 ± 0.519.6 ± 1.1761 ± 83−55.9 ± 1.547 ± 6−17.9 ± 2.0115.2 ± 2.04.2 ± 0.4−20.0 ± 1.218
Small IB4-positive neurons
    WT21.3 ± 0.721.9 ± 1.2575 ± 86−57.7 ± 1.5149 ± 19−14.3 ± 2.0115.4 ± 2.25.9 ± 0.6−19.1 ± 1.217
    KO21.8 ± 0.724.3 ± 1.7627 ± 81−54.7 ± 1.1128 ± 17−11.4 ± 2.4114.8 ± 2.95.7 ± 0.4−21.9 ± 1.519