Table 1.

Specific recommendations from workshop participants

• Development of tools for labeling/manipulating astrocytes in the living retina
• Gene expression profiling of glial cell types during gliosis
• A better understand of Müller cell roles in creating and maintaining ECM and retinal health
• Examination of the transcription factors/signaling mechanisms that control microglial state changes
• Methods to label resident and systemic immune cells acutely in order to examine morphology during disease (ideally suitable for use in humans)
• Further understanding of microglia signaling mechanisms during aging and disease
• Methods to make transplanted cells less adherent to CSPGs at scarred sites
• Further development of ECM scaffolds to promote regeneration or integration of transplanted cells
• The ability to manipulate the blood-retina barrier in a region-specific manner for targeted delivery of therapeutic agents