Diffusion values for clusters displaying significant increases in MD or FA during the interictal phase in migraineurs compared with controls
| Brain region | Diffusivity parameter | Controls | Interictal | Immediately prior to migraine | Immediately following migraine |
|---|---|---|---|---|---|
| Left PAG/CNF | MD | 0.86 ± 0.01 | 0.92 ± 0.01 | 0.89 ± 0.01 | 0.93 ± 0.02 |
| Axial diffusivity | 1.07 ± 0.02 | 1.14 ± 0.01 | 1.12 ± 0.02 | 1.14 ± 0.02 | |
| Radial diffusivity | 0.75 ± 0.01 | 0.81 ± 0.01 | 0.79 ± 0.02 | 0.81 ± 0.02 | |
| FA | 0.28 ± 0.01 | 0.27 ± 0.01 | 0.27 ± 0.01 | 0.27 ± 0.01 | |
| left dlPons | MD | 0.77 ± 0.01 | 0.82 ± 0.01 | 0.79 ± 0.01 | 0.82 ± 0.01 |
| Axial diffusivity | 1.37 ± 0.02 | 1.44 ± 0.01 | 1.40 ± 0.02 | 1.45 ± 0.02 | |
| Radial diffusivity | 0.47 ± 0.01 | 0.51 ± 0.01 | 0.49 ± 0.01 | 0.50 ± 0.02 | |
| FA | 0.63 ± 0.01 | 0.61 ± 0.01 | 0.61 ± 0.01 | 0.63 ± 0.01 | |
| right dl/dmPons | MD | 0.83 ± 0.01 | 0.89 ± 0.1 | 0.86 ± 0.01 | 0.90 ± 0.01 |
| Axial diffusivity | 1.52 ± 0.02 | 1.61 ± 0.02 | 1.58 ± 0.02 | 1.64 ± 0.02 | |
| Radial diffusivity | 0.49 ± 0.01 | 0.54 ± 0.02 | 0.55 ± 0.03 | 0.53 ± 0.02 | |
| FA | 0.66 ± 0.01 | 0.65 ± 0.01 | 0.65 ± 0.02 | 0.66 ± 0.01 | |
| SpV | MD | 0.73 ± 0.01 | 0.79 ± 0.01 | 0.76 ± 0.1 | 0.78 ± 0.1 |
| Axial diffusivity | 1.04 ± 0.02 | 1.10 ± 0.01 | 1.06 ± 0.01 | 1.08 ± 0.01 | |
| Radial diffusivity | 0.59 ± 0.01 | 0.63 ± 0.01 | 0.61 ± 0.01 | 0.62 ± 0.01 | |
| FA | 0.37 ± 0.01 | 0.36 ± 0.01 | 0.37 ± 0.01 | 0.36 ± 0.01 | |
| VTT/VTA | MD | 0.90 ± 0.02 | 0.87 ± 0.02 | 0.84 ± 0.02 | 0.87 ± 0.01 |
| Axial diffusivity | 1.26 ± 0.02 | 1.25 ± 0.02 | 1.25 ± 0.02 | 1.29 ± 0.02 | |
| Radial diffusivity | 0.72 ± 0.02 | 0.67 ± 0.02 | 0.64 ± 0.03 | 0.67 ± 0.01 | |
| FA | 0.41 ± 0.01 | 0.45 ± 0.01 | 0.47 ± 0.02 | 0.47 ± 0.01 |
MD, axial diffusivity, and radial diffusivity values are expressed as x10−3. The gray shaded boxes indicate a significant difference compared with controls.