RNA sequencing indicates 14 kcnj and 15 kcnk potassium channels identified in the cortex of symptomatic MeCP2–/y mice and WT age-matched littermates
| Protein | Gene name | FPKM WT | FPKM TG | Fold change | q value | Cell type specificity |
|---|---|---|---|---|---|---|
| Kir4.1 | Kcnj10 | 80.991 | 65.281 | –0.311 | 0.00065 | Astrocytes/oligodendrocytes/OPCs |
| Kir5.1 | Kcnj16 | 14.832 | 11.353 | –0.386 | 0.00853 | Astrocytes/OPCs |
| TREK-1 | Kcnk2 | 25.299 | 31.559 | 0.319 | 0.03503 | Astrocytes/neurons/OPCs |
Only Kcnj10, Kcnj16 and Kcnk2 are differentially expressed (data mined from Pacheco et al., 2017).