Full dataset of expression of HD markers in the striatum of Q175 that are tested by using NanoString technology. Bold text indicates significant difference between ad lib and TRF feeding protocols
| Gene symbol | −Log (p value) | Log 2 Fold Change |
|---|---|---|
| Aco2 | 0.51 | −0.09 |
| Aif1 | 0.58 | 0.13 |
| Apba2bp | 0.60 | −0.37 |
| Arc | 2.58 | 0.11 |
| Bdnf | 0.54 | −0.56 |
| Bhlhb2 | 0.16 | −0.12 |
| C1qc | 0.17 | 0.14 |
| C3 | 0.49 | 0.05 |
| C4a | 0.60 | 0.08 |
| calb1 | 0.39 | 0.11 |
| Calm1 | 0.74 | 0.03 |
| Calm2 | 1.43 | −0.16 |
| Calm3 | 0.06 | −0.09 |
| Cdkn1c | 0.04 | −0.21 |
| Chat | 0.55 | 0.07 |
| Chga | 0.54 | −0.01 |
| Chrm1 | 0.33 | −0.13 |
| Chrm4 | 2.92 | 0.17 |
| Chrna4 | 1.43 | −0.15 |
| Chrnb2 | 0.62 | 0.07 |
| Cnr1 | 1.02 | 0.04 |
| Cth | 0.28 | 0.09 |
| Dnajb5 | 0.13 | −0.04 |
| Drd1a | 1.06 | 0.21 |
| Drd2 | 1.00 | 0.25 |
| Egr1 | 1.84 | 0.13 |
| Egr2 | 2.34 | 0.24 |
| Egr3 | 0.86 | 0.08 |
| Egr4 | 1.54 | 0.21 |
| F8a | 1.24 | −0.01 |
| Fos | 3.39 | 0.23 |
| Fth1 | 0.34 | 0.03 |
| Gabra1 | 0.43 | −0.02 |
| Gabrd | 0.05 | 0.11 |
| Gclc | 1.74 | 0.15 |
| Gclm | 0.07 | −0.08 |
| Gfap | 1.03 | 0.03 |
| Grm2 | 1.59 | −0.47 |
| Grm5 | 1.33 | 0.01 |
| Hace1 | 2.03 | −0.03 |
| Hmox1 | 0.86 | 0.20 |
| Hrh3 | 3.04 | 0.31 |
| Htr1a | 0.03 | −0.36 |
| Htr1b | 1.22 | 0.27 |
| Htr2a | 3.32 | 0.15 |
| Htt | 0.50 | −0.10 |
| Il12b | 0.73 | 0.04 |
| Il6 | 0.41 | −0.16 |
| Kcnip2 | 1.05 | 0.10 |
| Lonp1 | 0.67 | 0.05 |
| Nfe2l2 | 0.01 | −0.05 |
| Ngf | 0.75 | −0.26 |
| Nos1 | 0.96 | 0.02 |
| Nos3 | 0.09 | 0.10 |
| Npy | 2.35 | −0.02 |
| Nqo1 | 0.90 | 0.03 |
| Ntrk1 | 1.18 | 0.13 |
| Ntrk2 | 1.12 | −0.09 |
| Pde10a | 0.97 | 0.20 |
| Pde9a | 1.59 | 0.02 |
| (Continued) | ||
| pdyn | 1.89 | 0.22 |
| Penk | 1.82 | 0.26 |
| Penk1 | 1.80 | 0.23 |
| Per2 | 2.50 | −0.01 |
| Ppargc1a | 0.08 | 0.05 |
| Ppp1r1b | 1.61 | 0.19 |
| Ptpn5 | 0.76 | 0.09 |
| Pvalb | 1.42 | 0.02 |
| Rgs4 | 0.09 | 0.00 |
| Rrs1 | 0.88 | 0.16 |
| Ryr1 | 0.15 | −0.14 |
| Sap25 | 0.72 | 0.03 |
| Slc17a6 | 1.81 | −0.15 |
| Slc17a7 | 0.10 | −0.70 |
| Slc1a2 | 0.12 | −0.09 |
| Slc6a3 | 0.78 | 0.16 |
| Slco6b1 | 0.61 | 0.41 |
| Snap25 | 0.12 | −0.08 |
| Sod1 | 1.01 | 0.01 |
| Sod2 | 0.00 | 0.05 |
| Sst | 1.96 | 0.17 |
| Tac1 | 1.09 | 0.15 |
| Tacr1 | 2.71 | 0.33 |
| Tfeb | 0.98 | 0.03 |
| Tmsb10 | 0.05 | 0.24 |
| Vgf | 0.69 | 0.08 |
| hHTT polypro | 0.01 | −0.12 |
| mHTT polypro | 0.15 | −0.01 |