Comparisons of age-matched WT under ad lib to regimen (n = 8/group)
| WT TRF | WT TRF vs WT ad lib | ||
|---|---|---|---|
| Locomotor activity rhythm | AVG ± SEM | Difference | p value |
| Rhythmic power (V%) | 57.03 ± 3.15 | 24.44 | <0.001 |
| Cage activity (a.u/h) | 269.96 ± 20.24 | 117.49 | <0.001 |
| Onset variability (min) | 31.54 ± 2.49 | 8.34 | 0.028U |
| Bouts/d | 6.8 ± 0.38 | −1.64 | 0.009 |
| Average bout length (rest-phase) | 202.55 ± 25.87 | 35.74 | 0.313 |
| Sleep behavior rhythm | |||
| Daily sleep | 646.25 ± 31.61 | −19.17 | 0.598 |
| Bouts/d | 9.5 ± 0.61 | 1.06 | 0.279 |
| Average bout length (night) | 60.06 ± 12.8 | −25.47 | 0.326 |
| Awake time (ZT) | 11.90 ± 0.16 | −0.12 | 0.095 |
| Awake deviation time I (min) | 19.57 ± 6.04 | 5.94 | 0.42 |
| Motor performance | |||
| Latency to fall (sec) | 457.08 ± 22.12 | 136.43 | <0.001 |
| Crossing errors (#) | 3.28 ± 0.31 | 0.19 | 0.6 |
| Body weight (g) | 29.02 ± 0.87 | −0.76 | 0.343 |
Find the values of ad lib in Table 2. The results of t tests are reported if data passed normality tests. DF = 14. For parameters that did not pass normality tests, the Mann–Whitney rank-sum test was run and the U statistic reported; p < 0.05 was considered significant.