Layer | EPSC charge | EPSC frequency | EPSC amplitude | IPSC charge | IPSC frequency | IPSC amplitude | E/I ratio | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
bDEOP17 | bDEOP21 | bDEOP17 | bDEOP21 | bDEOP17 | bDEOP21 | bDEOP17 | bDEOP21 | bDEOP17 | bDEOP21 | bDEOP17 | bDEOP21 | bDEOP17 | bDEOP21 | |
L2/3 | 51 ± 5; *p = 0.01 | 126 ± 22; p = 0.5 | 64 ± 7; *p = 0.04 | 107 ± 14; p = 0.8 | 88 ± 7; p = 0.3 | 116 ± 10; p = 0.3 | 63 ± 9; *p = 0.03 | 90 ± 13; p = 0.8 | 77 ± 7; p = 0.1 | 94 ± 12; p = 0.8 | 84 ± 5; *p = 0.04 | 104 ± 7; p = 0.8 | 83.6 ± 12.1 p = 0.5 | 134.8 ± 24.8 p = 0.3 |
L4 | 60 ± 9; *p = 0.03 | 128 ± 25; p = 0.3 | 57 ± 9; *p = 0.01 | 118 ± 21; p = 0.6 | 105 ± 8; p = 0.6 | 106 ± 6; p = 0.3 | 64 ± 6; *p = 0.01 | 99 ± 10; p = 0.9 | 70 ± 8; *p = 0.02 | 99 ± 8; p = 0.9 | 94 ± 5; p = 0.5 | 107 ± 2; p = 0.2 | 83.0 ± 9.5p = 0.4 | 130.6 ± 23.4p = 0.3 |
L5 | 59 ± 8; *p = 0.03 | 122 ± 30; p = 0.5 | 63 ± 9; *p = 0.03 | 107 ± 23; p = 0.8 | 95 ± 7; p = 0.7 | 99 ± 11; p = 0.9 | 59 ± 10; *p = 0.02 | 101 ± 20; p = 0.9 | 56 ± 6; *p = 0.01 | 105 ± 13; p = 0.8 | 96 ± 7; p = 0.7 | 99 ± 7; p = 0.9 | 119.8 ± 26.9p = 0.5 | 131.4 ± 43.8p = 0.5 |
L6 | 82 ± 16; p = 0.5 | 106 ± 18; p = 0.8 | 65 ± 11; p = 0.2 | 84 ± 21; p = 0.6 | 111 ± 6; p = 0.2 | 117 ± 10; p = 0.1 | 77 ± 12; p = 0.3 | 114 ± 18; p = 0.1 | 60 ± 9; p = 0.07 | 93 ± 14; p = 0.4 | 114 ± 9; p = 0.1 | 116 ± 8; p = 0.1 | 91.9 ± 13.5; p = 0.7 | 94.3 ± 9.6; p = 0.8 |
Results are expressed as mean % change from control (age-matched littermates) ± SEM. *Statistically significant (p < 0.05) by t test.