Heat rate and heart rate variability (HRV) in mice that survived SE.
| Time | Control (n = 6) | Pilo-SE (n = 8) | ||||
|---|---|---|---|---|---|---|
| Heart rate (bpm) | SDNN (ms) | RMSSD (ms) | Heart rate (bpm) | SDNN (ms) | RMSSD (ms) | |
| Baseline | 539.42 ± 14.23 | 10.60 ± 0.13 | 2.96 ± 0.65 | 525.8 ± 22.02 | 10.77 ± 0.21 | 3.22 ± 0.38 |
| 24 h | 534.66 ± 8.92 | 10.68 ± 0.08 | 3.37 ± 0.51 | 636.10 ± 39.12 | 9.85 ± 0.34 | 2.86 ± 0.59 |
| Week 6 | 549.96 ± 12.93 | 10.48 ± 0.13 | 3.21 ± 1.25 | 556.90 ± 26.26 | 10.47 ± 0.23 | 3.32 ± 0.45 |
| Week 12 | 530.54 ± 9.28 | 10.68 ± 0.09 | 3.12 ± 0.66 | 524.10 ± 18.19 | 10.75 ± 0.19 | 3.27 ± 0.62 |
Heart rate and the standard deviation of the N-to-N interval (SDNN) were increased 24 h after SE, but no differences were detected at other time points (heart rate: two-way ANOVA, F(3,46) = 2.52, p = 0.069; SDNN: two-way ANOVA, F(3,46) = 2.25, p = 0.094). The root mean squared of the standard deviation (RMSSD) was not significantly different at any time point (two-way ANOVA, F(3,46) = 0.135, p = 0.939).