Table 1.

Output and input projections to D2R-expressing neurons in the PVT

Output projectionsInput projections
AI++
PL++
Orbital frontal cortex++
Cingulate cortex+
NAc (core and shell)++
Caudate putamen++
BNST++
Lateral septum+
IPAC++
AmygdalaCentral, lateral, basolateralCentral
Zona incerta+
Reticular thalamus+
Hypothalamus: preoptic, ventromedial, anterior, lateral, posterior, dorsomedial, arcuate, suprachiasmatic, paraventricular, A14, and supramammillary nuclei+
PAG+
VTA+
SN+
LC+
LPBN+
Raphe (dorsal and raphe magnus)+
  • Al, agranular insular cortex; PL, prelimbic cortex; NAc, nucleus accumbens; BSNT, bed nucleus of the stria terminalis; IPAC, interstitial nucleus of the posterior limb of the anterior commissure; PAG, periaqueductal gray; VTA, ventral tegmental area; SN, substantia nigra; LC, locus coeruleus; LPBN, lateral parabrachial nucleus.