Table 1.

The basic membrane properties of untransfected and gene transfected hippocampal CA1 neurons

Cell typesPeak amplitude of AP (mV)Resting membrane potential (mV)Input resistance (MΩ)Series resistance (MΩ)Number of cells/mice
untrans106.1 ± 1.331−55.87 ± 0.900105.6 ± 8.4528.127 ± 0.276845/8
pSup108.5 ± 2.452−58.51 ± 1.604122.9 ± 18.628.869 ± 0.609313/7
shScr109.3 ± 1.456−57.47 ± 1.104143.1 ± 18.038.456 ± 0.390220/5
shLuc106.0 ± 2.224−57.07 ± 1.054131.0 ± 11.299.349 ± 0.311022/9
Statistics p valueshLuc vs shScr 0.7606shLuc vs shScr >0.9999shLuc vs shScr 0.9893shLuc vs shScr 0.4875
shLuc vs pSup 0.9657shLuc vs pSup 0.9777shLuc vs pSup 0.9996shLuc vs pSup 0.9755
shLuc vs untrans >0.9999shLuc vs untrans 0.9604shLuc vs untrans 0.567shLuc vs untrans 0.0681
shScr vs untrans 0.6744shScr vs pSup 0.9958shScr vs pSup 0.9434shScr vs pSup 0.988
shScr vs pSup >0.9999shScr vs untrans 0.8504shScr vs untrans 0.1487shScr vs untrans 0.9813
pSup vs untrans 0.9603pSup vs untrans 0.5991pSup vs untrans 0.9558pSup vs untrans 0.7507
  • Note that all of these parameters were not statistically different between four cell groups. Statistics were done by one-way ANOVA with post hoc Tukey.