Table 2.

Proportional difference in expression of all 48 genes in Hcrt/Ox and MCH neurons

Gene symbolProportion in MCH neuronsProportion in Hcrt/Ox neuronsAbsolute proportional difference (%)Adjusted p value
Pdyn1/8969/6999.05.12E-43*
Lhx93/8969/6997.02.18E-40*
Hcrt5/8969/6994.03.93E-38*
Pmch89/896/6991.01.59E-36*
Igfbp320/8969/6978.06.90E-26*
Th14/8960/6971.01.84E-19*
Nptx229/8969/6967.07.82E-21*
Nkx2.154/890/6961.09.11E-18*
Nnat39/8968/6955.01.78E-14*
Penk26/8953/6948.01.43E-08*
Rbfox386/8937/6943.01.81E-10*
Gad187/8939/6941.01.87E-10*
Slc17a88/8933/6939.01.30E-07*
Pnoc31/890/6935.05.08E-09*
Nucb268/8969/6924.06.23E-06*
Cartpt59/8929/6924.09.39E-03*
Sst0/8914/6920.01.21E-05*
Gal49/8949/6916.0>0.05
Calb176/8969/6915.01.70E-03*
Calb280/8968/699.0>0.05
Ghsr2/897/698.0>0.05
Mc4r27/8916/697.0>0.05
Slc18a10/894/696.0>0.05
Pvalb2/896/696.0>0.05
Nts16/898/696.0>0.05
Tac16/898/695.0>0.05
Gad219/8911/695.0>0.05
Tph10/892/693.0>0.05
Slc17a687/8969/692.0>0.05
Ada2/890/692.0>0.05
Lepr6/893/692.0>0.05
Crh16/8911/692.0>0.05
S100b16/8911/692.0>0.05
Gfap4/892/692.0>0.05
Slc32a10/891/691.0>0.05
Map288/8969/691.0>0.05
Tph21/890/691.0>0.05
Trh7/896/691.0>0.05
Slc18a22/891/691.0>0.05
Hprt89/8969/690.0>0.05
Gapdh89/8969/690.0>0.05
Slc17a70/890/690.0>0.05
Hdc0/890/690.0>0.05
Tac20/890/690.0>0.05
Tubb389/8969/690.0>0.05
Gls89/8969/690.0>0.05
Chat0/890/690.0>0.05
Celf689/8969/690.0>0.05
  • Asterisks (*) denote significant difference (Fisher’s exact text and Benjamini-Hochberg procedure to control FDR at 5%).