Table 1.

Statistical table

DescriptionData structureType of testStatistical value
asIPSC frequency (Fig. 1B)Normal distributiont testt(29) = 0.5388, p = 0.5941 (3–4 weeks); t(29) = 2.116, p = 0.0431 (6–8 weeks)
bsIPSC amplitude (Fig. 1C)Normal distributiont test; ANOVAt(29) = 0.5665, p = 0.5754 (3–4 weeks); t(29) = 0.4330, p = 0.6682 (6–8 weeks); age: F(1,58) = 20.27, p < 0.0001
csIPSC rise time (Fig. 1E)Normal distributionANOVAF(1,60) = 2.188, p = 0.1443 (WT vs KO)
dsIPSC decay time (Fig. 1F)Normal distributionANOVAF(1,60) = 0.7872, p = 0.3785 (WT vs KO)
eIGABA in six to eight weeks (Fig. 2B)Non-normal distributionM–W testp = 0.0282
fCm in IGABA measurementNormal distributiont testt(36) = 0.4044, p = 0.6883
gNormalized IGABA in six to eight weeks (Fig. 2C)Non-normal distributionM–W testp = 0.0058
hIGABA in three to four weeks (Fig. 2B)Normal distributiont testt(31) = 0.4277, p = 0.8637
iNormalized IGABA in three to four weeks (Fig. 2C)Non-normal distributionM–W testp = 0.5529
jCm in ITHIP measurementNormal distributiont testt(45) = 0.1597, p = 0.8739
kITHIP (Fig. 3B)Normal distributiont testt(45) = 2.788, p = 0.0077
lNormalized ITHIP (Fig. 3C)Normal distributiont testt(45) = 2.979, p = 0.0047
mCm in IBaclofen measurementNormal distributiont testt(28) = 1.533, p = 0.1366
nIBaclofen (Fig. 4B)Normal distributiont testt(28) = 1.182, p = 0.247
oNormalized IBaclofen (Fig. 4C)Non-normal distributionM–W testp = 0.9834
pRamp-current threshold (Fig. 5A)Normal distributiont testt(23) = 0.1924, p = 0.849 (3–4 weeks); t(22) = 1.064, p = 0.299 (6–8 weeks)
qCurrent-firing curve (Fig. 5B)ANOVAF(1,23) = 0.0228, p = 0.881 (3–4 weeks); F(1,22) = 1.320, p = 0.263, (6–8 weeks)
rStep-current threshold (Fig. 5C)Normal distributiont testt(23) = 0.2003, p = 0.843 (3–4 weeks); t(22) = 0.8177, p = 0.4223 (6–8 weeks)
sMax. firing rate (Fig. 5D)Normal distributiont testt(23) = 0.69, p = 0.4971 (3–4 weeks); t(22) = 0.9258, p = 0.3646 (6–8 weeks)
tCurrent-firing curve in three to four weeks (Fig. 6B)ANOVAF(1,24) = 28.45, p < 0.0001 (WT, before vs THIP); F(1,24) = 14.66, p = 0.0008 (KO, before vs THIP); F(1,24) = 1.199, p = 0.2844 (before, WT vs KO); F(1,24) = 0.0073, p = 0.9328 (THIP, WT vs KO)
uCurrent-firing curve in six to eight weeks (Fig. 6C)ANOVAF(1,30) = 57.87, p < 0.0001 (WT, before vs THIP); F(1,32) = 30.66, p = 0.0008 (KO, before vs THIP); F(1,31) = 1.228, p = 0.2764 (before, WT vs KO); F(1,31) = 4.919, p = 0.0340 (THIP, WT vs KO)
vStep-current threshold (Fig. 6D)Normal distribution
Non-normal distribution
Paired t test
Wilcoxon test
t(12) = 7.229, p < 0.0001 (WT); p = 0.0005(KO)
wStep-current threshold (Fig. 6E)Non-normal distribution
Normal distribution
Wilcoxon test
Paired t test
p < 0.0001 (WT);
t(16) = 6.154, p < 0.0001 (KO)
xΔ current threshold (Fig. 6F)Non-normal distributionM–W testp = 0.0257
ySlope in three to four weeks (Fig. 6G)Non-normal distributionWilcoxon testp = 0.0002 (WT)
p = 0.0002 (KO)
zSlope in six to eight weeks (Fig. 6H)Normal distribution
Non-normal distribution
Paired t test
Wilcoxon test
t(15) = 5.761, p < 0.0001 (WT); p = 0.0001 (KO)
aaΔ slope (Fig. 6I)Non-normal distributionM–W testp = 0.0063