Effects of germline Cre recombination on incidence of epileptiform events
| Cre genotype | tTA genotype | GCaMP genotype | Incidence with germline Cre recombination | Incidence without germline Cre recombination |
|---|---|---|---|---|
| Emx1 | Camk2a | Ai93 | 9/10 | 30/44 |
| Ntsr1 | Camk2a | Ai93 | 5/9 | |
| Rbp4 | Camk2a | Ai93 | 4/4 | 0/11 |
| Rorb | Camk2a | Ai93 | 5/8 | 0/3 |
“With germline Cre recombination”, mice that had lost Cre conditionality; “without”, mice that were normal, i.e. expressed GCaMP only in subsets of neurons according to the Cre driver line used. In this table, all mice were imaged with widefield calcium imaging of any size window.