Table 1.

TFs associated with regeneration whose expression is also impacted by the GR (transcriptionally activated/repressed by GR)

Transcription factorEffect of GR on transcription
C/EBPα+
C/EBPβ+
COUP-TFII+
c-Rel (NF-κB subunit)+
HIF1A+
IRF1+
NURR1+
p73+
PPAR-γ+
SF1+
STAT3+
STAT5+
STAT5A+
STAT5B+
TBP+
c-Jun/c-Fos-
c-Rel (NF-κB subunit)-
E2A-
NF-AT2(NFATC1)-
NF-κB-
NF-κB1 (p50)-
p53-
p73-
PIT1-
RelA (p65 NF-κB subunit)-
SMAD3-
STAT6-
T-bet-
ZNF307-
  • Interactions were determined using MetaCore software and were identified in mouse, rat, and human.