Table 2.

Fos-ir in primary and bystander mice

Brain areaControlPrimaryBystanderANOVA
Anterior cingulate (CG1)156.6 ± 14.28220.8 ± 28.66251.9 ± 20.18*F(2,14) = 4.77
Anterior cingulate (CG2)73.56 ± 5.6575.14 ± 20.0577.33 ± 14.12F(2,15) = 0.017
GranularInsula (GI)19.08 ± 2.75223.89 ± 2.69524.46 ± 6.201F(2,16) = 0.547
Agranular insula (INS)36.1 ± 3.7350.86 ± 9.03273.02 ± 15.59*F(2,15) = 3.779
Somatosensory542.1 ± 44.79659.8 ± 168.7449.6 ± 76.52F(2,16) = 1.147
Dorsal lateral septum6.893 ± 1.5426.958 ± 2.0216.5 ± 1.351F(2,17) = 0.023
Intermediate lateral septum23.82 ± 2.32623.71 ± 1.42919.44 ± 2.637F(2,17) = 1.250
Ventral lateral septum13.65 ± 0.99114.36 ± 3.34212.27 ± 2.743F(2,17) = 0.183
Nucleus accumbens21.65 ± 6.32325.76 ± 5.95923.02 ± 3.265F(2,16) = 0.155
Bed nucleus of the stria terminalis (anterior)30.89 ± 2.248 ± 11.139.14 ± 5.47F(2,17) = 1.561
Bed nucleus of the stria terminalis (posterior)20.53 ± 8.44425.45 ± 2.9123.33 ± 4.889F(2,15) = 1.472
Dentate gyrus36.19 ± 5.33739.14 ± 6.74431.27 ± 6.609F(2,17) = 0.4011
Posterolateral cortical amygdaloid24.69 ± 2.32817.3 ± 3.41216.6 ± 1.027F(2,16) = 2.845
Posteromedial cortical amygdaloid9.571 ± 1.8527.571 ± 1.2428.722 ± 0.604F(2,17) = 0.5452
Basolateral amygdala12.61 ± 12.6112.13 ± 2.59217.78 ± 4.901F(2,15) = 0.7956
Central nucleus of the amygdala9.063 ± 1.1945.833 ± 1.15310.02 ± 2.409F(2,15) = 1.687
Paraventricular nucleus3.4 ± 0.7511.17 ± 3.5512.13 ± 3.29F(2,12) = 2.584
Dorsal medial hypothalamus16.15 ± 2.25130.59 ± 5.143**20.73 ± 2.242F(2,16) = 4.842
Centrally projecting Edinger Westphal7.988 ± 1.27612.16 ± 3.07311.38 ± 1.799F(2,17) = 1.150
Periaqueductal gray44.98 ± 7.04979.96 ± 19.1463.9 ± 8.827F(2,17) = 2.073
Substantia nigra4.679 ± 2.2987.917 ± 2.5466.107 ± 1.603F(2,17) = 0.5495
Ventral tegmental area2.93 ± 1.024.88 ± 2.549.43 ± 4.66F(2,15) = 1.115
  • Mean (±SEM) c-Fos-positive cell counts for experimental each group per brain area examined. ANOVA values are presented in the right column, with significant main effects of group in bold. *p < 0.05 contrast to controls, Fishers LSD.