Table 1.

Significant increase in the protein levels of various inflammatory mediators in the hippocampus of TMEV-infected mice during acute seizure activity period. Statistics: Two-way ANOVA, Bonferroni posttest, #p<0.05, *p<0.01, p<0.001; SEM, standard error of the mean. (TNFα, tumor necrosis factor-α; IFNγ, interferon-γ; IL, interleukin; CXCL1, C-X-C motif chemokine ligand 1)

Fold change (relative to PBS-injected control mice)
1 dpi (n = 8)5 dpi (n = 6)14 dpi (n = 5)
CytokineAverageSEMAverageSEMAverageSEM
TNFα6.90.6206.214.934.8#7.1
IFNγ4.50.821,734.43123.299.121.6
IL-1β6.91.158.25.446.613.5
IL-102.30.347.26.09.61.9
IL-12p702.50.33.0#0.56.01.0
IL-41.00.20.80.11.30.3
IL-22.40.314.44.24.90.7
IL-52.00.110.8*2.52.61.2
CXCL14.60.330.04.32.40.3
  • Statistics: two-way ANOVA, Bonferroni posttest, p<0.001; #p<0.05; *p<0.01. CXCL1, C-X-C motif chemokine ligand 1.