Table 3.

Summary of results (part II)

ParameterMain effects (two-way ANOVA)Group differences (from NaCl-Social)
TreatmentRearingInteractionNaCl-IsolationMK801-SocialMK801-Isolation
Structure of pyramidal neurons (Fig. 5)
    Dendritic spines
        PFC
            50(28)
            100n/an/an/a
            150(29)n/an/an/a
            200(30)n/an/an/a
            Totaln/an/an/a
Structure of interneurons (Fig. 6)
    Dendritic arborization
        Amygdala
            20#(31)(32)
            40(33)(34)*
            60(35)(36)(37)***
            80(38)(39)(40)*
            100(41)(42)#(43)n/an/an/a
            120(44)(45)(46)*
            140#(47)n/an/an/a
            160n/an/an/a
            Total(48)(49)(50)***
        PFC
            20n/an/an/a
            40n/an/an/a
            60n/an/an/a
            80n/an/an/a
            100n/an/an/a
            120n/an/an/a
            140n/an/an/a
            160n/an/an/a
            Totaln/an/an/a
    Dendritic spines
        Amygdala
            50n/an/an/a
            100n/an/an/a
            150#(51)#(52)n/an/an/a
            Totaln/an/an/a
        PFC
            50#(53)(54)#(55)n/an/an/a
            100(56)(57)(58)*****
            150(59)(60)n/an/an/a
            Total(61)(62)(63)********
  • Symbols: (✓) statistically significant effect (two-way ANOVA); (—) no statistically significant effect (two-way ANOVA) or difference from NaCl-Social group (post hoc); (↑) increase; (n/a) not applicable; (↓) decrease; *p < 0.05; **p < 0.01; ***p < 0.001; #0.10 ≥ p ≥ 0.05.

  • F and p values: (28) F(1,15) = 6.29, p = 0.024; (29) F(1,15) = 4.88, p = 0.043; (30) F(1,18) = 4.90, p = 0.043 (31) F(1,19) = 3.81, p = 0.066; (32) F(1,19) = 4.72, p = 0.043; (33) F(1,19) = 9.02, p = 0.007; (34) F(1,19) = 12.58, p = 0.002; (35) F(1,18) = 7.53, p = 0.013; (36) F(1,18) = 23.53, p = 12.8 × 10−5; (37) F(1,18) = 12.62, p = 0.002; (38) F(1,19) = 4.64, p = 0.044; (39) F(1,19) = 6.55, p = 0.019; (40) F(1,19) = 10.23, p = 0.005; (41) F(1,20) = 4.43, p = 0.048; (42) F(1,20) = 8.79, p = 0.008; (43) F(1,20) = 3.27, p = 0.086; (44) F(1,20) = 5.73, p = 0.027; (45) F(1,20) = 5.32, p = 0.032; (46) F(1,20) = 14.63, p = 0.0011; (47) F(1,20) = 4.34, p = 0.050; (48) F(1,20) = 8.31, p = 0.009; (49) F(1,20) = 14.29, p = 0.001; (50) F(1,20) = 18.23, p = 37.5 × 10−5; (51) F(1,22) = 3.79, p = 0.064; (52) F(1,22) = 3.34, p = 0.081; (53) F(1,22) = 3.74, p = 0.066; (54) F(1,22) = 4.53, p = 0.045; (55) F(1,22) = 3.31, p = 0.083; (56) F(1,22) = 11.72, p = 0.002; (57) F(1,22) = 5.50, p = 0.029; (58) F(1,22) = 5.18, p = 0.033; (59) F(1,22) = 5.50, p = 0.028; (60) F(1,22) = 7.43, p = 0.012; (61) F(1,22) = 21.08, p = 14.2 × 10−5; (62) F(1,22) = 6.27, p = 0.020; (63) F(1,22) = 10.18, p = 0.004.