Table 2.

Summary of results (part I)

ParameterMain effects (two-way ANOVA)Group differences (from NaCl-Social)
TreatmentRearingInteractionNaCl-IsolationMK801-SocialMK801-Isolation
Behavior (Figs. 2, 3)
    Locomotor activity
        Total distance travelled
            Gad-EGFP mice(1)n/an/an/a
            Thy1-YFP mice(2)(3)(4)**
        Mean speed
            Gad-EGFP mice(5)n/an/an/a
            Thy1-YFP mice(6)(7)(8)**
    Anxiety-related behavior
        Border distance
            Gad-EGFP mice(9)n/an/an/a
            Thy1-YFP mice(10)(11)n/an/an/a
        Border entries
            Gad-EGFP mice(12)n/an/an/a
            Thy1-YFP mice(13)(14)(15)*
        Body rotations
            Gad-EGFP mice(16)n/an/an/a
            Thy1-YFP mice(17)(18)(19)*******
    Exploratory behavior
            Gad-EGFP micen/an/an/a
            Thy1-YFP micen/an/an/a
Brain volume (Fig. 4)
    Amygdala
        Total volume#(20)n/an/an/a
        Central(21)*
        Lateraln/an/an/a
        Basolateral(22)n/an/an/a
        Basomedial(23)n/an/an/a
        Medialn/an/an/a
    PFC
        Total volume#(24)n/an/an/a
        IL#(25)n/an/an/a
        PrLn/an/an/a
        Cg1(26)(27)#
        Cg2n/an/an/a
  • Symbols: (✓) statistically significant effect (two-way ANOVA); (—) no statistically significant effect (two-way ANOVA) or difference from NaCl-Social group (post hoc); (↑) increase; (n/a) not applicable; (↓) decrease; *p < 0.05; **p < 0.01; ***p < 0.001; #0.10 ≥ p ≥ 0.05.

  • F and p values: (1) F(1,58) = 31.11, p < 10−6; (2) F(1,11) = 8.05, p = 0.016; (3) F(1,11) = 9.99, p = 0.009; (4) F(1,11) = 6.74, p = 0.025; (5) F(1,59) = 19.38, p = 4.6 × 10−5; (6) F(1,11) = 7.80, p = 0.018; (7) F(1,11) = 9.90, p = 0.009; (8) F(1,11) = 6.61, p = 0.026; (9) F(1,59) = 36.48, p < 10−7; (10) F(1,11) = 8.22, p = 0.015; (11) F(1,11) = 20.68, p = 0.001; (12) F(1,60) = 6.20, p = 0.016; (13) F(1,11) = 7.48, p = 0.019; (14) F(1,11) = 6.11, p = 0.031; (15) F(1,11) = 8.27, p = 0.015; (16) F(1,60) = 5.14, p = 0.027; (17) F(1,11) = 93.50, p = 10−5; (18) F(1,11) = 119.86, p < 10 − 6; (19) F(1,11) = 42.94, p = 4.1 × 10−5; (20) F(1,20) = 3.34, p = 0.082; (21) F(1,21) = 4.73, p = 0.041; (22) F(1,21) = 9.44, p = 0.0058; (23) F(1,21) = 5.82, p = 0.025; (24) F(1,23) = 3.39, p = 0.079; (25) F(1,23) = 3.61, p = 0.07; (26) F(1,22) = 5.062, p = 0.035; (27) F(1,22) = 6.62, p = 0.017.