Table 2.

Summary of results (part I)

Parameter	Main effects (two-way ANOVA)			Group differences (from NaCl-Social)
Parameter	Treatment	Rearing	Interaction	NaCl-Isolation	MK801-Social	MK801-Isolation
Behavior (Figs. 2, 3)
Locomotor activity
Total distance travelled
Gad-EGFP mice	—	✓⁽¹⁾	—	n/a	n/a	n/a
Thy1-YFP mice	✓⁽²⁾	✓⁽³⁾	✓⁽⁴⁾	—	—	↑^**
Mean speed
Gad-EGFP mice	—	✓⁽⁵⁾	—	n/a	n/a	n/a
Thy1-YFP mice	✓⁽⁶⁾	✓⁽⁷⁾	✓⁽⁸⁾	—	—	↑^**
Anxiety-related behavior
Border distance
Gad-EGFP mice	—	✓⁽⁹⁾	—	n/a	n/a	n/a
Thy1-YFP mice	✓⁽¹⁰⁾	✓⁽¹¹⁾	—	n/a	n/a	n/a
Border entries
Gad-EGFP mice	—	✓⁽¹²⁾	—	n/a	n/a	n/a
Thy1-YFP mice	✓⁽¹³⁾	✓⁽¹⁴⁾	✓⁽¹⁵⁾	—	—	↑^*
Body rotations
Gad-EGFP mice	—	✓⁽¹⁶⁾	—	n/a	n/a	n/a
Thy1-YFP mice	✓⁽¹⁷⁾	✓⁽¹⁸⁾	✓⁽¹⁹⁾	↑^***	↑^*	↑^***
Exploratory behavior
Gad-EGFP mice	—	—	—	n/a	n/a	n/a
Thy1-YFP mice	—	—	—	n/a	n/a	n/a
Brain volume (Fig. 4)
Amygdala
Total volume	—	—	^#⁽²⁰⁾	n/a	n/a	n/a
Central	—	—	✓⁽²¹⁾	↑^*	—	—
Lateral	—	—	—	n/a	n/a	n/a
Basolateral	—	✓⁽²²⁾	—	n/a	n/a	n/a
Basomedial	✓⁽²³⁾	—	—	n/a	n/a	n/a
Medial	—	—	—	n/a	n/a	n/a
PFC
Total volume	—	^#⁽²⁴⁾	—	n/a	n/a	n/a
IL	—	^#⁽²⁵⁾	—	n/a	n/a	n/a
PrL	—	—	—	n/a	n/a	n/a
Cg1	✓⁽²⁶⁾	—	✓⁽²⁷⁾	—	—	↓^#
Cg2	—	—	—	n/a	n/a	n/a

↵Symbols: (✓) statistically significant effect (two-way ANOVA); (—) no statistically significant effect (two-way ANOVA) or difference from NaCl-Social group (post hoc); (↑) increase; (n/a) not applicable; (↓) decrease; *p < 0.05; **p < 0.01; ***p < 0.001; #0.10 ≥ p ≥ 0.05.
F and p values: (1) F_(1,58) = 31.11, p < 10⁻⁶; (2) F_(1,11) = 8.05, p = 0.016; (3) F_(1,11) = 9.99, p = 0.009; (4) F_(1,11) = 6.74, p = 0.025; (5) F_(1,59) = 19.38, p = 4.6 × 10⁻⁵; (6) F_(1,11) = 7.80, p = 0.018; (7) F_(1,11) = 9.90, p = 0.009; (8) F_(1,11) = 6.61, p = 0.026; (9) F_(1,59) = 36.48, p < 10⁻⁷; (10) F_(1,11) = 8.22, p = 0.015; (11) F_(1,11) = 20.68, p = 0.001; (12) F_(1,60) = 6.20, p = 0.016; (13) F_(1,11) = 7.48, p = 0.019; (14) F_(1,11) = 6.11, p = 0.031; (15) F_(1,11) = 8.27, p = 0.015; (16) F_(1,60) = 5.14, p = 0.027; (17) F_(1,11) = 93.50, p = 10⁻⁵; (18) F_(1,11) = 119.86, p < 10 − 6; (19) F_(1,11) = 42.94, p = 4.1 × 10⁻⁵; (20) F_(1,20) = 3.34, p = 0.082; (21) F_(1,21) = 4.73, p = 0.041; (22) F_(1,21) = 9.44, p = 0.0058; (23) F_(1,21) = 5.82, p = 0.025; (24) F_(1,23) = 3.39, p = 0.079; (25) F_(1,23) = 3.61, p = 0.07; (26) F_(1,22) = 5.062, p = 0.035; (27) F_(1,22) = 6.62, p = 0.017.