Table 5.

Summary of results (part IV)

ParameterMain effects (two-way ANOVA)Group differences (from NaCl-Social)
TreatmentRearingInteractionNaCl-IsolationMK801-SocialMK801-Isolation
Protein expression (Fig.7)
    GAD67
        Amygdala(98)n/an/an/a
        PFCn/an/an/a
    SYN
        Amygdalan/an/an/a
        PFCn/an/an/a
    PSA-NCAM
        Amygdala(99)(100)#(101)n/an/an/a
        PFC(102)n/an/an/a
Gene expression (Fig.7)
    GAD67
        Amygdalan/an/an/a
        PFC#(103)n/an/an/a
    BDNF
        Amygdalan/an/an/a
        PFC(104)n/an/an/a
    ErbB4
        Amygdala#(105)n/an/an/a
        PFCn/an/an/a
    CB1-R
        Amygdala(106)n/an/an/a
        PFCn/an/an/a
    ST8SiaII
        Amygdala#(107)n/an/an/a
        PFCn/an/an/a
    ST8SiaIV
        Amygdalan/an/an/a
        PFC#(108)(109)n/an/an/a
  • Symbols: (✓) statistically significant effect (two-way ANOVA); (—) no statistically significant effect (two-way ANOVA) or difference from NaCl-Social group (post hoc); (↑) increase; (n/a) not applicable; (↓) decrease; (*) p < 0.05; (**) p < 0.01; (***) p < 0.001; (#) 0.10 ≥ p ≥ 0.05.

  • F and p values: (98) F(1,19) = 11.74, p = 0.003; (99) F(1,25) = 11.58, p = 0.002; (100) F(1,25) = 107.23, p < 10−10; (101) F(1,25) = 4.02, p = 0.056; (102) F(1,32) = 9.863, p = 0.004; (103) F(1,25) = 3.94, p = 0.058; (104) F(1,26) = 13.51, p = 0.001; (105) F(1,25) = 4.10, p = 0.054; (106) F(1,26) = 5.52, p = 0.027; (107) F(1,20) = 3.07, p = 0.095; (108) F(1,25) = 4.12, p = 0.053; (109) F(1,25) = 5.06, p = 0.033.