Comparison of passive membrane and AP properties between NMc1/NMc2 and mid- to high-CF NM neurons
| Property | NMc1/NMc2 (n) | Mid- to high-CF NMa | P, t test |
|---|---|---|---|
| Passive membrane properties | |||
| RMP (mV)b | –50.55 ± 9.74 (30) | –66.52 ± 8.49 (28) | <0.0001 |
| Time constant tau (ms) | 20.39 ± 17.25 (29) | 3.18 ± 1.33 (20) | <0.0001 |
| Input resistance (MΩ) | 467.2 ± 342.5 (29) | 123.90 ± 49.90 (20) | <0.0001 |
| Membrane capacitance (pF) | 41.25 ± 21.74 (29) | 26.15 ± 4.60 (20) | <0.01 |
| Action potential properties | |||
| Threshold current (pA) | 38.96 ± 25.96 (22) | 321.70 ± 121.00 (28) | <0.0001 |
| Max rise rate (mV/ms) c | 136.1 ± 41.01 (22) | 155.60 ± 42.19 (28) | 0.107 |
| Max fall rate (mV/ms) c | –69.14 ± 22.16 (22) | –104.40 ± 29.79 (28) | <0.0001 |
| AP half width (ms) c | 1.45 ± 0.48 (22) | 0.97 ± 0.17 (28) | <0.0001 |
| AP reliability range (ms)c | 6.98 ± 5.87 (17)d | 0.21 ± 0.14 (28) | <0.0001 |
↵a Data from Hong et al., 2016. Experimental conditions (e.g., temperature) and recording parameters (e.g., membrane capacitance) for both studies are the same.
↵b Numeric values without the correction of –10 mV junction potential.
↵c Measured from APs in response to current injections 25% above threshold current.
↵d Five outliner neurons with reliability range >30 ms were removed.