Varenicline
TrpB* | EC50 (μM) | nH | Fold shift | N |
---|---|---|---|---|
Trp | 0.0024 ± 0.0001 | 1.2 ± 0.1 | 1 | 15 |
F1Trp | 0.0057 ± 0.0002 | 1.2 ± 0.1 | 2.4 | 11 |
F2Trp | 0.0057 ± 0.0021 | 1.2 ± 0.1 | 2.4 | 14 |
F3Trp | 0.027 ± 0.001 | 1.3 ± 0.1 | 11 | 12 |
F4Trp | 0.056 ± 0.005 | 1.1 ± 0.1 | 23 | 14 |
TyrC2 | EC50 (μM) | nH | Imax (μA) | Fold shift | N |
---|---|---|---|---|---|
Phe | 0.0014 ± 0.0002 | 1.3 ± 0.14 | 0.04–0.14 | 1 | 10 |
F1Phe | 0.0020 ± 0.00009 | 1.5 ± 0.09 | 0.02–0.08 | 1.4 | 8 |
F2Phe | 0.011 ± 0.00097 | 1.2 ± 0.11 | 0.02–0.1 | 8.1 | 12 |
F3Phe | 0.027 ± 0.0016 | 1.1 ± 0.06 | 0.02–0.09 | 19 | 8 |