Metanicotine
TrpB | EC50 (μM) | nH | Imax (μA) | Fold shift | N |
---|---|---|---|---|---|
Trp | 0.64 ± 0.02 | 1.3 ± 0.0 | 0.08–0.89 | 1 | 13 |
F1Trp | 0.79 ± 0.02 | 1.4 ± 0.0 | 0.12–0.80 | 1.2 | 16 |
F2Trp | 3.6 ± 0.1 | 1.5 ± 0.1 | 0.15–0.56 | 5.6 | 14 |
F3Trp | 13 ± 1 | 1.6 ± 0.1 | 0.07–0.30 | 20 | 12 |
F4Trp | 16 ± 2 | 1.3 ± 0.1 | 0.03–0.11 | 25 | 12 |
TyrA | EC50 (μM) | nH | Imax (μA) | Fold shift | N |
Phe | 19 ± 5 | 1.1 ± 0.2 | 0.02–0.16 | 1 | 7 |
F3Phe | 17 ± 2 | 1.3 ± 0.1 | 0.01–0.03 | 0.9 | 6 |
TyrC2 | EC50 (μM) | nH | Imax (μA) | Fold shift | N |
Phe | 0.41 ± 0.03 | 1.2 ± 0.07 | 0.06–2.78 | 1 | 17 |
F1Phe | 0.86 ± 0.06 | 1.2 ± 0.08 | 0.04–0.07 | 2.1 | 11 |
F2Phe | 11 ± 1 | 0.6 ± 0.1 | 0.03–0.13 | 27 | 8 |
F3Phe | 21 ± 1 | 1.4 ± 0.2 | 0.04–0.24 | 51 | 12 |