Statistics
| Figure | Data structure | Statistical test | Power/significance level |
|---|---|---|---|
| 1B | Normal distribution | Unpaired t test | 0.0317 |
| 2A | Normal distribution | Two-way ANOVA, Tukey’s test | Drug, 0.0032 KA-SE, 0.8793 Interaction, 0.064 |
| 2B | Normal distribution | Two-way ANOVA, Bonferroni’s test | Drug, 0.02080 KA-SE, 0.0705 Interaction, 0.0625 |
| 3A | Nonparametric | Mann–Whitney test | 0.2831 |
| 3B | Nonparametric | Mann–Whitney test | 0.0990 |
| 3C | Nonparametric | Mann–Whitney test | 0.3256 |
| 3D | Nonparametric | Mann–Whitney test | 0.1429 |
| 3E | Nonparametric | Mann–Whitney test | 0.7533 |
| 3G | Nonparametric | Mann–Whitney test | 0.9004 |
| 3H | Nonparametric | Mann–Whitney test | 0.4242 |
| 4A | Normal distribution | Two-way ANOVA, Tukey’s test | Drug, 0.4538 KA-SE, <0.0001 Interaction, 0.5467 |
| 4B | Normal distribution | Two-way ANOVA, Tukey’s test | Drug, 0.3588 KA-SE, 0.0002 Interaction, 0.1033 |
| 4C | Normal distribution | Two-way ANOVA, Tukey’s test | Drug, 0.3638 KA-SE, 0.1229 Interaction, 0.0579 |
| 4D | Normal distribution | Two-way ANOVA, Tukey’s test | Drug, 0.1461 KA-SE, 0.8726 Interaction, 0.0198 |