Table 1.

Plasma proteins that are uniquely associated with HI and LPS/HI brain injury at 24-h recovery

SymbolDescription (all in Mus musculus)Peptide feature countsCT/CT log2(ratio)CT/CT SD, n = 3LPS/CT log2(ratio)LPS/CT SD, n = 9HI/CT log2(ratio)HI/CT SD, n = 9LPS/HI/CT log2(ratio)LPS/HI/CT SD, n = 9
TUBA1BTubulin alpha-1B chain58–0.60.33–0.780.5–0.940.47–1.110.41
RELNReelin precursor180.010.22–0.570.35–0.960.27–1.050.14
MBL2Mannos-binding protein C precursor860.230.28–0.510.43–1.170.3–1.550.3
TAS1R3Taste receptor type 1 member 3 precursor5–0.350.17–0.770.43–1.220.53–1.380.56
IGFALSInsulin-like growth factor-binding protein complex acid labile subunit precursor171–0.110.26–0.560.18–1.780.34–2.060.31
IGFBP3Insulin-like growth factor-binding protein 3 precursor27––0.920.25–1.280.35
GDAGuanine deaminase150.250.360.620.341.030.451.050.49
OSTBOrganic solute transporter subunit beta80.420.140.790.290.90.311.050.33
STFA3Stefin-3 (cystatin C)14–0.480.990.620.682.630.711.670.6
MYO18BMyosin XVIIIb2–
SH3BGRLSH3 domain-binding glutamic acid-rich like protein30.331.21–0.091.981.860.841.70.76
DCPSm7GpppX diphosphatase120.20.350.340.451.550.611.470.32
PLEKHM1Pleckstrin homology domain-containing family M member 12–0.050.49–0.120.450.920.421.060.44
CYCSCytochrome c, somatic50–0.350.140.640.211.590.231.440.28
SCARB1Scavenger receptor class B member 1 isoform 12–
  • Plasma proteins associated with HI and LPS/HI brain injury at 24-h recovery in P10 mice. Proteomics detection and statistical analysis were performed as described in the text. Sixteen high-confidence proteins changing in this category with ≥2 MS/MS-identified peptide feature counts used for quantitation across the 12 samples are reported.