Kinases tested in the kinase assay.
| Kinase | Rank (phosphonet.ca) | Inhibition by staurosporine (%) |
|---|---|---|
| CK1a* | 1 | 20.29 |
| CK1d* | 10 | 8.77 |
| CK1e* | 11 | 21.79 |
| CK2a1* | NA | –0.64 |
| CK2a2* | NA | 33.38 |
| CDK7* | 2 | 56.22 |
| PKCg | 6 | 103.22 |
| PKCb | 9 | 95.87 |
| PKCa | 15 | 98.77 |
| PLK3 | 14 | 62.21 |
| GRK2* | 13 | 44.18 |
| Nuak2 | 4 | 79.77 |
| Erk1 | NA | 2.79 |
| Erk2 | NA | 2.55 |
| Jnk1 | NA | –2.48 |
| Jnk2 | NA | 0.00 |
| Jnk3 | NA | –23.23 |
The degree to which each kinase’s activity is inhibited by staurosporine is shown in the right column (according to ReactionBiology.com). *Kinase activity toward rFMRP S500 based on SDS-PAGE. NA, not applicable.