Function | Gene symbol | Gene name | Fold change | p-value |
---|---|---|---|---|
High in ipsilateral RGCs | ||||
Regulation of transcription | Atoh7 | Atonal homolog 7 (Math5) | 3.87 | 0.010 |
Gli3 | GLI-Kruppel family member GLI3 | 3.19 | 0.015 | |
Klf4 | Kruppel-like factor 4 | 7.38 | 0.002 | |
Lhx2 | LIM homeobox protein 2 | 4.72 | 0.009 | |
Neurod4 | Neurogenic differentiation 4 | 6.00 | 0.013 | |
Otx2 | Orthodenticle homolog 2 | 5.02 | 0.021 | |
Sox2 | SRY-box containing gene 2 | 7.47 | 0.029 | |
Sox9 | SRY-box containing gene 9 | 5.69 | 0.003 | |
Zic1 | Zinc finger protein of the cerebellum 1 | 5.67 | 0.002 | |
Zic2 | Zinc finger protein of the cerebellum 2 | 5.78 | 0.016 | |
Developmental signaling | Fzd5 | Frizzled homolog 5 | 5.04 | 0.024 |
Notch2 | Notch gene homolog 2 | 6.02 | 0.031 | |
Tgfb2 | Transforming growth factor, beta 2 | 6.36 | 0.005 | |
Axon guidance | Sema5b | Semaphorin 5B | 4.11 | 0.007 |
Cell cycle control | Ccnd2 | Cyclin D2 | 8.17 | 0.002 |
Other cellular functions | Gja1 | Gap junction protein, alpha 1 (connexin 43) | 17.60 | 0.001 |
Slc1a3 | Glial high affinity glutamate transporter | 9.47 | 0.002 | |
Slc2a1 | Facilitated glucose transporter | 3.19 | 0.016 | |
Slc6a4 | Serotonin transporter (Sert) | 4.49 | 0.004 | |
Sparc | Secreted acidic cysteine rich glycoprotein | 12.47 | 0.000 | |
High in contralateral RGCs | ||||
Regulation of transcription | Pou4f1 | POU domain, class 4, transcription factor 1 (Brn3a) | 2.20 | 0.001 |
Tbx20 | T-box 20 | 2.15 | 0.001 | |
Signaling | Bmper | BMP-binding endothelial regulator | 2.83 | 0.002 |
Axon guidance | Sema3e | Semaphorin 3E | 2.20 | 0.003 |
Sema7a | Semaphorin 7A | 2.03 | 0.022 |
Genes previously known to be differentially expressed in ipsilateral and contralateral RGCs are bolded (Zic2, SERT, Brn3a).