Statistics.
| Line | Location | Type of test | p-value |
|---|---|---|---|
| a | Table 2 | Two-tailed Mann-Whitney U test (gestation length) | 0.3 |
| b | Table 2 | Two-tailed unpaired t test (litter size) | 0.9 |
| c | Table 2 | Bonferroni’s post hoc test (body weight at P4) | 1.0 |
| d | Table 2 | Bonferroni’s post hoc test (body weight at P14) | 1.0 |
| e | Table 2 | Bonferroni’s post hoc test (body weight at P21) | 1.0 |
| f | Table 2 | Bonferroni’s post hoc test (body weight at P28) | 1.0 |
| g | Table 2 | Bonferroni’s post hoc test (body weight at P60) | 1.0 |
| h | Fig. 2A | Two-way repeated-measures ANOVA (stimulus duration) | F(7,203) = 13.2; p < 0.0001 |
| i | Fig. 2A | Two-way repeated-measures ANOVA (treatment) | F(1,29) = 6.9; p = 0.01 |
| j | Fig. 2A | Bonferroni’s post hoc test at 8 s | p = 0.04 |
| k | Fig. 2A | Bonferroni’s post hoc test at 1 s | p = 0.0001 |
| l | Fig. 2B | Two-way repeated-measures ANOVA (stimulus duration) | F(7,203) = 178.2; p < 0.0001 |
| m | Fig. 2B | Two-way repeated-measures ANOVA (treatment) | F(1,29) = 2.3; p = 0.1 |
| n | Fig. 2B | Two-way repeated-measures ANOVA (stimulus duration X treatment) | F(7,203) = 5.3; p < 0.0001 |
| o | Fig. 2B | Bonferroni’s post hoc test at 8 s | p <0.0001 |
| p | Fig. 2C | Two-way repeated-measures ANOVA (stimulus duration) | F(7,203) = 26.7, p < 0.0001 |
| q | Fig. 2C | Two-way repeated-measures ANOVA (treatment) | F(1,29) = 0.2; p = 0.6 |
| r | Fig. 2C | Two-way repeated-measures ANOVA (stimulus duration × treatment) | F(7,203) = 2.8; p = 0.009 |
| s | Fig. 2C | Bonferroni’s post hoc test at 8 s | p = 0.005 |
| t | Fig. 2D | Two-way repeated-measures ANOVA (stimulus duration) | F(7,203) = 38.4; p < 0.0001 |
| u | Fig. 2D | Two-way repeated-measures ANOVA (treatment) | F(1,29) = 7.1; p = 0.01 |
| v | Fig. 2D | Two-way repeated-measures ANOVA (stimulus duration × treatment) | F(7,203) = 3.2; p = 0.003 |
| w | Fig. 2D | Bonferroni’s post hoc test at 1.2 s | p = 0.04 |
| x | Fig. 2D | Bonferroni’s post hoc test at 1.0 s | p < 0.0001 |
| y | Fig. 2E | Two-way repeated-measures ANOVA (stimulus duration) | F(7,203) = 58.6; p < 0.0001 |
| z | Fig. 2E | Two-way repeated-measures ANOVA (treatment) | F(1,29) = 0.8; p = 0.4 |
| aa | Fig. 2F | Two-way repeated-measures ANOVA (stimulus duration) | F(7,203) = 430.1; p < 0.0001 |
| ab | Fig. 2F | Two-way repeated-measures ANOVA (treatment) | F(1,29) = 0.01; p = 0.9 |
| ac | Fig. 3A | Two-way repeated-measures ANOVA (stimulus duration) | F(7,203) = 73.1; p < 0.0001 |
| ad | Fig. 3A | Two-way repeated-measures ANOVA (treatment) | F(1,29) = 1.3; p = 0.3 |
| ae | Fig. 3A | Two-way repeated-measures ANOVA (stimulus duration × treatment) | F(7,203) = 2.5; p = 0.02) |
| af | Fig. 3A | Bonferroni’s post hoc test at 8 s | p = 0.001 |
| ag | Fig. 3B | Two-way repeated-measures ANOVA (stimulus duration) | F(7,203) = 42.8; p < 0.0001 |
| ah | Fig. 3B | Two-way repeated-measures ANOVA (treatment) | F(1,29) = 5.6; p = 0.03 |
| ai | Fig. 3B | Bonferroni’s post hoc test at 1.6 s | p = 0.02 |
| aj | Fig. 3B | Bonferroni’s post hoc test at 1.0 s | p = 0.04 |
| ak | Table 3 | Two-tailed Mann-Whitney U test (capacitance) | p = 0.002 |
| al | Table 3 | Two-tailed Mann-Whitney U test (input resistance) | p = 0.09 |
| am | Table 3 | Two-tailed Mann-Whitney U test (resting membrane potential) | p = 0.5 |
| an | Table 3 | Two-tailed Mann-Whitney U test (spike amplitude) | p = 0.8 |
| ao | Fig. 4A | Two-tailed unpaired t test | p = 0.009 |
| ap | Fig. 4B | Two-way repeated-measures ANOVA (current injected × treatment) | F(10,1930) = 4.7; p < 0.0001 |
| aq | Fig. 4B (rising phase) | Two-way repeated-measures ANOVA (current injected) | F(3,579) = 922.1; p < 0.0001 |
| ar | Fig. 4B (rising phase) | Two-way repeated-measures ANOVA (treatment) | F(1,193) = 4.9; p = 0.03 |
| as | Fig. 4B (rising phase) | Two-way repeated-measures ANOVA (current injected × treatment) | F(3,579) = 2.3; p = 0.07 |
| at | Fig. 4B (descending phase) | Two-way repeated-measures ANOVA (current injected) | F(3,579) = 144.3; p < 0.0001 |
| au | Fig. 4B (descending phase) | Two-way repeated-measures ANOVA (treatment) | F(1,193) = 4.2, p = 0.04 |
| av | Fig. 4B (descending phase) | Two-way repeated-measures ANOVA (current injected × treatment) | F(3,579) = 0.3; p = 0.8 |
| aw | Fig. 4D | Two-way repeated-measures ANOVA on log-transformed data (current injected) | F(1,174) = 56.4; p < 0.0001 |
| ax | Fig. 4D | Two-way repeated-measures ANOVA on log-transformed data (treatment) | F(1,174) = 5.2; p = 0.02 |
| ay | Fig. 4D | Two-way repeated-measures ANOVA on log-transformed data (current injected × treatment) | F(1,174) = 0.04; p = 0.8 |
| az | Fig. 4D | Two-tailed Mann-Whitney U test (at 100 pA) | p = 0.03 |
| ba | Fig. 4D | Two-tailed Mann-Whitney U test (at 250 pA) | p = 0.04 |
| bb | Fig. 5A | Two-tailed unpaired t test | p = 0.01 |
| bc | Fig. 5B | Two-tailed Mann-Whitney U test | p = 0.008 |
| bd | Fig. 5C1 | Two-way repeated-measures ANOVA (time) | F(11,1419) = 30.5; p < 0.0001 |
| be | Fig. 5C1 | Two-way repeated-measures ANOVA (treatment) | F(1,1419) = 35.8; p < 0.0001 |
| bf | Fig. 5C2 | Two-tailed unpaired t test | p = 0.01 |
| bg | Fig. 5C3 | Two-tailed Mann-Whitney U test | p = 0.01 |
| bh | Table 4 | Two-tailed Mann-Whitney U test (frequency) | p = 0.6 |
| bi | Table 4 | Two-tailed Mann-Whitney U test (amplitude) | p = 0.08 |
| bj | Table 4 | Two-tailed Mann-Whitney U test (10–90 rise) | p = 0.0008 |
| bk | Table 4 | Two-tailed Mann-Whitney U test (10–90 slope) | p = 0.02 |
| bl | Table 4 | Two-tailed Mann-Whitney U test (decay) | p = 0.9 |
| bm | Fig. 7A | Two-tailed Mann-Whitney U test | p = 0.1 |
| bn | Fig. 7B | Two-tailed unpaired t test | p = 0.04 |
| bo | Fig. 7C1 | Two-way repeated-measures ANOVA (time) | F(11,311) = 4.0; p < 0.0001 |
| bp | Fig. 7C1 | Two-way repeated-measures ANOVA (treatment) | F(1,311) = 5.4; p = 0.02 |
| bq | Fig. 7C2 | Two-tailed unpaired t test | p = 0.6 |
| br | Fig. 7C3 | Two-tailed unpaired t test | p = 0.047 |
| bs | Table 5 | Two-tailed Pearson correlation coefficient | As indicated |
| bt | Table 6 | Two-tailed Pearson correlation coefficient | As indicated |