Table 1:

Statistical table

	Data structure	Type of test	Power (α = 0.05)	p value
a (Figs. 1I, 2G)	Normality assumed (Levene’s test p = 0.118)	One-way ANOVA with Bonferroni’s multiple-comparisons post hoc	0.9403	PirB^+/+ Cre⁺ vs PirB^−/− Cre⁺, p = 0.004; PirB^+/+ Cre⁺ vs PirB^fl/fl Cre⁺, p = 0.041; PirB^fl/fl Cre⁺ vs PirB^−/− Cre⁺, p = 1.000
b (Figs. 1J and 2H)	Normality assumed (Levene’s test p = 0.233)	One-way ANOVA with Bonferroni’s multiple-comparisons post hoc	0.9733	PirB^+/+ Cre⁺ vs PirB^−/− Cre⁺, p = 0.002; PirB^+/+ Cre⁺ vs PirB^fl/fl Cre⁺, p = 0.02; PirB^fl/fl Cre⁺ vs PirB^−/− Cre⁺, p = 1.000
c (Fig. 1K)	Normal distribution	Two-way ANOVA with repeated measures	0.2383	0.2443
d (Fig. 1L)	Normal distribution	Two-way ANOVA with repeated measures	0.9534	0.0574
e (Fig. 2K)	Normal distribution	Two-way ANOVA with repeated measures	0.0501	0.8864
f (Fig. 2L)	Normal distribution	Two-way ANOVA with repeated measures	0.0521	0.7799
g (Fig. 3C)	Normality assumed (Levene’s test p = 0.494)	One-way ANOVA with Bonferroni’s multiple-comparisons post hoc	0.9988	PirB^+/+ Cre⁺ vs PirB^fl/fl Cre⁺, p = 0.924; PirB^+/+ Cre⁺ vs PirB^−/− Cre⁺, p = 1.000; PirB^fl/fl Cre⁺ vs PirB^−/− Cre⁺, p = 1.000; P23 PirB^+/+ vs P30 PirB^+/+, p = 0.004; P23 PirB^fl/fl vs P30 PirB^fl/fl, p = 0.19; P23 PirB^−/− vs P30 PirB^−/−, p = 1.00
h (Fig. 4G)	Normality not assumed	Mann–Whitney	0.8509	0.0058
i (Fig. 4I)	Normality not assumed	Mann–Whitney	0.1634	0.3286
j (Fig. 4K)	Normality not assumed	Mann–Whitney	0.0961	0.4940
k (Fig. 4M)	Normality not assumed	Mann–Whitney	0.1855	0.3918
l (Fig. 5E)	Normality not assumed	Wilcoxon signed-rank	0.9959	0.0060
m (Fig. 5F)	Normality not assumed	Wilcoxon signed-rank	0.1109	0.7722
n (Fig. 6C)	Normality assumed (Levene’s test p = 0.869)	One-Way ANOVA with Bonferroni’s multiple comparisons post hoc	0.1347	PirB^+/+ Cre⁺ vs PirB^fl/fl Cre⁺, p = 1.000; PirB^+/+ Cre⁺ vs PirB^−/− Cre⁺, p = 1.000; PirB^fl/fl Cre⁺ vs PirB^−/− Cre⁺, p = 1.000