Table 6.

List of proteins identified in three independent proteomic studies: human and mouse cortex (current study) and whole mouse brain (McClure-Begley et al., 2013) (GN, gene name)

AccessionDescriptionNo. of experiments (found/total)
ACHA4Neuronal acetylcholine receptor subunit α4 GN = Chrna40/411
ACHB2Neuronal acetylcholine receptor subunit β2 GN = Chrnb20/411
ADT1ADP/ATP translocase 1 GN = Slc25a4195/411
ADT2ADP/ATP translocase 2 GN = Slc25a5223/411
AT1A3Sodium/potassium-transporting ATPase subunit α3 GN = Atp1a3101/411
AT1B1Sodium/potassium-transporting ATPase subunit β1 GN = Atp1b11/411
ATPAATP synthase subunit α, mito GN = Atp5a1210/411
ATPBATP synthase subunit β, mito GN = Atp5b211/411
CALMCalmodulin GN = Calm1133/411
EAA2Excitatory amino acid transporter 2 GN = Slc1a22/411
G3PGlyceraldehyde-3-phosphate dehydrogenase GN = GAPDH248/411
GBB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit β1 GN = Gnb159/411
GFAPGlial fibrillary acidic protein GN = GFAP73/411
GNAOGuanine nucleotide-binding protein G(o) subunit α GN = Gnao142/411
KCC2ACalcium/calmodulin-dependent protein kinase type II subunit α GN = CaMKIIa7/411
KCC2BCalcium/calmodulin-dependent protein kinase type II subunit β GN = CaMKIIb7/411
MBPMyelin basic protein GN = Mbp0/411
MPCPPhosphate carrier protein, mito GN = Slc25a3130/411
MYH10Myosin-10 GN = Myh10166/411
MYL6Myosin light polypeptide 6 GN = Myl6190/411
NDUS3NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mito GN = Ndufs319/411
NDUV2NADH dehydrogenase [ubiquinone] flavoprotein 2, mito GN = Ndufv23/411
NFLNeurofilament light polypeptide GN = NeflNot in database
NFMNeurofilament medium polypeptide GN = Nefm85/411
ODO2Dihydrolipoyllysine-res succinyltransferase 2-oxoglutarate dehydrogenase complex, mito GN = Dlst57/411
SNP25Synaptosomal-associated protein 25 GN = Snap250/411
SPTB2Spectrin β chain, nonerythrocytic 1 GN = Sptbn1143/411
SPTN1Spectrin α chain, nonerythrocytic 1 GN = Sptan1161/411
STX1BSyntaxin-1B GN = Stx1b0/411
SYT1Synaptotagmin-1 GN = Syt10/411
TBA4ATubulin α4A chain GN = Tuba4a377/411
TBB2ATubulin β2A chain GN = Tubb2a372/411
TBB3Tubulin β3 chain GN = Tubb3Not in database
TBB4ATubulin β4A chain GN = Tubb4a366/411
TBB4BTubulin β4B chain GN = Tubb4b376/411
TBB5Tubulin β5 chain GN = Tubb5Not in database
VATAV-type proton ATPase catalytic subunit A GN = Atp6v1a62/411
  • Numbers in the right hand column represent the number of times each protein has been identified in control studies designed to evaluate background contaminants (Mellacheruvu et al., 2013).