Fig. | Description | Data structure | Test | Factor | Degrees of freedom | Statistics value | p value | |
---|---|---|---|---|---|---|---|---|

a | 1C | Discrimination index | Normal distribution | Generalized linear mixed models | Novelty condition × data type interaction | 1,72 | F = 4.568 | 0.036 |

Novelty condition | 1, 72 | F = 5.289 | 0.024 | |||||

Data type | 1, 72 | F = 9.430 | 0.003 | |||||

Discrimination index in Session 2 of all conditions | Normal distribution | Repeated measures ANOVA | Novelty condition | 3, 21 | F = 4.175 | 0.018Post hoc:NO+NL vs F, p = 0.020;NL vs F, p = 0.108;NO vs F, p = 0.299;NO+NL vs NL, p = 0.223;NO+NL vs NO, p = 0.037 | ||

Discrimination index in control sessions | Normal distribution | Repeated-measures ANOVA | Novelty condition | 3, 21 | F = 1.809 | 0.176 | ||

Discrimination index in NO+NL condition | Normal distribution | Paired t test | Data type | 9 | t = 4.751 | 0.001 | ||

Discrimination index in NL condition | Normal distribution | Paired t test | Data type | 7 | t = 1.345 | 0.221 | ||

Discrimination index in NO condition | Normal distribution | Paired t test | Data type | 9 | t = 1.259 | 0.240 | ||

Discrimination index in F condition | Normal distribution | Paired t test | Data type | 9 | t = 0.393 | 0.703 | ||

b | 1D | Exploration time in Session 1 | Normal distribution | Repeated-measures ANOVA | Novelty condition | 3,21 | F = 1.216 | 0.329 |

c | 2D,3D | Hippocampal gamma power change over running speed in novel and familiar conditions | Normal distribution | Generalized linear mixed models | Running speed | 1,5450 | F = 2.609 | 0.106 |

Brain region | 1,5450 | F = 85.640 | <0.001 | |||||

Object–place pairing type | 1,5450 | F = 99.128 | <0.001 | |||||

Gamma type | 1,5450 | F = 66.361 | <0.001 | |||||

Hippocampal gamma power change in novel and familiar conditions | Normal distribution | Generalized linear mixed models | Interaction: brain region × novelty condition × object–place pairing type × gamma type | 1,164 | F = 3.984 | 0.048 | ||

Object–place pairing type | 1,164 | F = 7.500 | 0.007 | |||||

Gamma type | 1,164 | F = 3.938 | 0.049 | |||||

d | 2D | CA1 gamma power change between novel and familiar conditions | Normal distribution | Generalized linear mixed models | Interaction: novelty condition × object–place pairing type × gamma type | 1,104 | F = 11.953 | 0.001 |

CA1 gamma power change between NO+NL and F conditions | Binomial distribution | Binomial test | N/A | N/A | Fast gamma power change: Object C: p = 0.021;Object A: p = 0.109;Slow gamma power change: Object C: p = 0.754;Object A: p = 0.754 | |||

CA1 gamma power change between NO+NL and F conditions | Normal distribution | Generalized linear mixed models | Interaction: object–place pairing type × gamma type | 1,36 | F = 6.941 | 0.012Post hoc:Fast gamma: Obj A vs C, p = 0.011;Slow gamma: Obj A vs C, p = 0.791 | ||

CA1 gamma power change between NL and F conditions | Binomial distribution | Binomial test | N/A | N/A | Fast gamma power change: Object A’: p =0.008;Object A: p =0.289;Slow gamma power change: Object A’: p =1.000;Object A: p = 0.289 | |||

CA1 gamma power change between NL and F conditions | Normal distribution | Generalized linear mixed models | Interaction: object–place pairing type × gamma type | 1,28 | F = 6.109 | 0.020Post hoc:Fast gamma: Obj A vs A’, p = 0.169;Slow gamma: Obj A vs A’, p = 0.226 | ||

CA1 gamma power change between NO and F conditions | Binomial distribution | Binomial test | N/A | N/A | Fast gamma power change: Object B: p = 0.109;Object A: p = 0.109;Slow gamma power change: Object B: p = 0.754;Object A: p = 0.754 | |||

CA1 gamma power change between NO and F conditions | Normal distribution | Generalized linear mixed models | Object–place pairing type | 1,36 | F = 1.406 | 0.243 | ||

Gamma type | 1,36 | F = 3.174 | 0.083 | |||||

Interaction: object–place pairing type × gamma type | 1,36 | F = 0.054 | 0.817Post hoc:Fast gamma: Obj A vs B, p = 0.090;Slow gamma: Obj A vs B, p = 0.025 | |||||

CA1 gamma power change between novel and familiar conditions, using stricter criterion of exploration | Normal distribution | Generalized linear mixed models | Interaction: novelty condition × object–place pairing type × gamma type | 1,104 | F = 5.087 | 0.026 | ||

CA1 gamma power change between NO+NL and F conditions, using stricter criterion of exploration | Binomial distribution | Binomial test | N/A | N/A | Fast gamma power change: Object C: p = 0.021;Object A: p = 0.344;Slow gamma power change: Object C: p = 0.344;Object A: p = 1.000 | |||

CA1 gamma power change between NO+NL and F conditions, using stricter criterion of exploration | Normal distribution | Generalized linear mixed models | Interaction: object–place pairing type × gamma type | 1,36 | F = 3.953 | 0.054Post hoc:Fast gamma: Obj A vs C, p = 0.016;Slow gamma: Obj A vs C, p = 0.354 | ||

CA1 gamma power change between NL and F conditions, using stricter criterion of exploration | Normal distribution | Generalized linear mixed models | Interaction: object–place pairing type × gamma type | 1,28 | F = 4.241 | 0.049Post hoc:Fast gamma: Obj A vs A’, p = 0.060;Slow gamma: Obj A vs A’, p = 0.806 | ||

CA1 gamma power change between NO and F conditions, using stricter criterion of exploration | Normal distribution | Generalized linear mixed models | Object–place pairing type | 1,36 | F = 0.527 | 0.473 | ||

Gamma type | 1,36 | F = 0.068 | 0.796 | |||||

Interaction: object–place pairing type × gamma type | 1,36 | F = 0.107 | 0.745Post hoc:Fast gamma: Obj A vs B, p = 0.129;Slow gamma: Obj A vs B, p = 0.224 | |||||

e | 3D | CA3 gamma power change between NO+NL and F conditions | Binomial distribution | Binomial test | N/A | N/A | Fast gamma power change: Object C: p = 0.219;Object A: p = 0. 219;Slow gamma power change: Object C: p = 0.219;Object A: p = 1.000 | |

CA3 gamma power change between NL and F conditions | Binomial distribution | Binomial test | N/A | N/A | Fast gamma power change: Object A’: p = 0.625;Object A: p = 0.625;Slow gamma power change: Object A’: p = 0.625;Object A: p = 0.625 | |||

CA3 gamma power change between NO and F conditions | Binomial distribution | Binomial test | N/A | N/A | Fast gamma power change: Object B: p = 0.219;Object A: p = 0.688;Slow gamma power change: Object B: p = 0.688;Object A: p = 1.000 | |||

CA3 gamma power change between novel and familiar conditions | Normal distribution | Generalized linear mixed models | Interaction: novelty condition × object–place pairing type × gamma type | 1,56 | F = 1.138 | 0.291 | ||

Interaction: object–place pairing type × gamma type | 1,56 | F = 1.161 | 0.286 | |||||

Novelty condition | 1,56 | F = 0.266 | 0.608 | |||||

Object–place pairing type | 1,56 | F = 0.984 | 0.325 | |||||

Gamma type | 1,56 | F = 0.520 | 0.474 | |||||

CA3 gamma power change between NO+NL and F conditions | Normal distribution | Generalized linear mixed models | Interaction: object–place pairing type × gamma type | 1,20 | F = 1.045 | 0.319Post hoc:Fast gamma: Obj A vs C, p = 0.372;Slow gamma: Obj A vs C, p = 0.589 | ||

f | 4 | Gamma phase synchrony change between novel and familiar object–place pairings | Normal distribution | Generalized linear mixed models | Interaction: novelty condition × gamma type | 1,40 | F = 11.005 | 0.002 |

Gamma phase synchrony difference (C–A) | Normal distribution | Paired t test | Gamma type | 5 | t = 4.316 | 0.008 | ||

Gamma phase synchrony difference (A’–A) | Normal distribution | Paired t test | Gamma type | 3 | t = 0.420 | 0.703 | ||

Gamma phase synchrony difference (B–A) | Normal distribution | Paired t test | Gamma type | 5 | t = 1.707 | 0.148 | ||

g | 5 | Mean vector length of gamma phase distributions | Normal distribution | Generalized linear mixed models | Interaction: novelty condition × cell type × gamma type | 1,398 | F = 3.980 | 0.047 |

5A | Mean vector length of gamma phase distributions in NO+NL condition | Normal distribution | Generalized linear mixed models | Interaction: cell type × gamma type | 1,110 | F = 4.812 | 0.030Post hoc:Fast gamma: cells A vs cells C, p = 0.008;Slow gamma: cells A vs cells C, p = 0.928 | |

5B | Mean vector length of gamma phase distributions in NL condition | Normal distribution | Generalized linear mixed models | Interaction: cell type × gamma type | 1,100 | F = 4.136 | 0.045Post hoc:Fast gamma: cells A vs cells A’, p = 0.159;Slow gamma: cells A vs cells A’, p = 0.428 | |

5C | Mean vector length of gamma phase distributions in NO condition | Normal distribution | Generalized linear mixed models | Interaction: cell type × gamma type | 1,132 | F = 0.416 | 0.520Post hoc:Fast gamma: cells A vs cells B, p = 0.049;Slow gamma: cells A vs cells B, p = 0.163 | |

h | 6D | Place cell in-field firing rates in all novel conditions | Normal distribution | Generalized linear mixed models | Interaction: novelty condition × cell type × gamma type | 1,146 | F = 0.549 | 0.460 |

Interaction: cell type × gamma type | 1,146 | F = 4.538 | 0.035 | |||||

Place cell in-field firing rates in NO+NL condition | Normal distribution | Generalized linear mixed models | Interaction: cell type × gamma type | 1,56 | F = 4.507 | 0.038Post hoc (sign test):Cell C: slow vs fast gamma, p = 0.039;Cell A: slow vs fast gamma, p = 0.238 | ||

Place cell in-field firing rates in NL condition | Normal distribution | Generalized linear mixed models | Interaction: cell ype × gamma type | 1,38 | F = 33.532 | <0.001Post hoc (sign test):Cell A’: slow vs fast gamma, p < 0.008;Cell A: slow vs fast gamma, p = 0.092 | ||

Place cell in-field firing rates in NO condition | Normal distribution | Generalized linear mixed models | Interaction: cell type × gamma type | 1,48 | F = 1.322 | 0.256 | ||

Cell type | 1,48 | F = 0.015 | 0.902 | |||||

Gamma type | 1,48 | F = 0.005 | 0.942 | |||||

i | 6E | Place cell in-field firing rates in NO+NL condition (gamma detected by non-local EEG) | Normal distribution | Sign test | Gamma type | N/A | N/A | Cell C: slow vs fast gamma, p = 0.039;Cell A: slow vs fast gamma, p = 0.481 |

Place cell in-field firing rates in NL condition (gamma detected by non-local EEG) | Normal distribution | Sign test | Gamma type | N/A | N/A | Cell A’: slow vs fast gamma, p = 0.070;Cell A: slow vs fast gamma, p = 0.267 | ||

j | 7D,E | Hippocampal theta power change between novel and familiar conditions | Normal distribution | Generalized linear mixed models | Interaction: brain region × novelty condition × object–place pairing type | 1,80 | F = 0.001 | 0.976 |

7D | CA1 theta power change between novel and familiar conditions | Normal distribution | Generalized linear mixed models | Interaction: novelty condition × object–place pairing type | 1,52 | F = 3.410 | 0.070 | |

CA1 theta power change between NO+NL and F conditions | Normal distribution | Paired t test | Object–place pairing type | 9 | t = 1.317 | 0.220 | ||

CA1 theta power change between NL and F conditions | Normal distribution | Paired t test | Object–place pairing type | 7 | t = 1.986 | 0.087 | ||

CA1 theta power change between NO and F conditions | Normal distribution | Paired t test | Object–place pairing type | 9 | t = 0.041 | 0.968 | ||

7E | CA3 theta power change between novel and familiar conditions | Normal distribution | Generalized linear mixed models | Interaction: novelty condition × object–place pairing type | 1,28 | F = 0.650 | 0.427 | |

CA3 theta power change between NO+NL and F conditions | Normal distribution | Paired t test | Object–place pairing type | 5 | t = 1.934 | 0.111 | ||

CA3 theta power change between NL and F conditions | Normal distribution | Paired t test | Object–place pairing type | 3 | t = 1.109 | 0.348 | ||

CA3 theta power change between NO and F conditions | Normal distribution | Paired t test | Object–place pairing type | 5 | t = 1.849 | 0.124 | ||

N/A | Hippocampal theta power change between novel and familiar conditions, using stricter criterion of exploration | Normal distribution | Generalized linear mixed models | Interaction: brain region × novelty condition × object–place pairing type | 1,80 | F = 0.049 | 0.825 | |

CA1 theta power change between novel and familiar conditions, using stricter criterion of exploration | Normal distribution | Generalized linear mixed models | Interaction: novelty condition × object–place pairing type | 1,52 | F = 0.013 | 0.910 | ||

CA1 theta power change between NO+NL and F conditions, using stricter criterion of exploration | Normal distribution | Paired t test | Object–place pairing type | 9 | t = 1.287 | 0.230 | ||

CA1 theta power change between NL and F conditions, using stricter criterion of exploration | Normal distribution | Paired t test | Object–place pairing type | 7 | t = 2.040 | 0.081 | ||

CA1 theta power change between NO and F conditions, using stricter criterion of exploration | Normal distribution | Paired t test | Object–place pairing type | 9 | t = 0.793 | 0.448 | ||

k | 7F | Theta phase synchrony change between novel and familiar object–place pairings | Normal distribution | Repeated-measures ANOVA | Novelty condition | 3,9 | F = 2.484 | 0.127 |

l | 7G | Mean vector length of theta phase distributions | Normal distribution | Two-way ANOVA | Interaction: novelty condition × cell type | 2,195 | F = 3.085 | 0.048 |

Mean vector length of theta phase distributions in NO+NL condition | Normal distribution | t test | cell type | 55 | t = 2.192 | 0.033 | ||

Mean vector length of theta phase distributions in NL condition | Normal distribution | t test | cell type | 50 | t = 0.808 | 0.423 | ||

Mean vector length of theta phase distributions in NO condition | Normal distribution | t test | cell type | 66 | t = 0.966 | 0.338 |