Data structure | Type of test | Confidence interval | ||||
---|---|---|---|---|---|---|

a | Normal distribution | t test | −6.78 to −3.94 | |||

b | Normal distribution | t test | −116.0 to −98.31 | |||

c | Non-normal distribution (Shapiro–Wilk test p < 0.05) | One-way ANOVA Kruskal–Wallis on ranks with a post hoc Tukey test | p < 0.01 ANOVA8 min vs baseline: p < 0.05 | |||

d | Non-normal distribution (Shapiro–Wilk test p < 0.05) | One-way ANOVA | Baseline vs 48 min: p > 0.05 | |||

e | Normal distribution | Unpaired t test | −23.76 to −15.36 | |||

f | Normal distribution | t test with Holm–Sidak for multiple comparisons | −245.2 to −110.5 | |||

g | Normal distribution | t test with Holm–Sidak for multiple comparisons | −64.78 to −20.95 | |||

h | Normal distribution | One-way ANOVA | WT vs WT+4-AP | −0.9128 to 0.1422 | ||

WT vs scn1Lab | −0.5763 to 0.4787 | |||||

WT vs scn1Lab+4-AP | −0.5664 to 0.4886 | |||||

i | Normal distribution | Two-way ANOVA | Complex I | −148.8 to 112.6 | ||

Complex II | −138.4 to 123.1 | |||||

Complex III | −177.9 to 83.56 | |||||

Complex IV | −146.6 to 114.9 | |||||

j | Normal distribution | Two-way ANOVA | Aconitase | −15.04 to 45.86 | ||

Fumarase | −32.52 to 28.38 | |||||

Mal. Dehyd. | −21.06 to 33.41 | |||||

k | Normal distribution | t test | −0.3722 to 3.172 | |||

l | Normal distribution | t test | 65.33 to 64.27 | |||

m | Normal distribution | t test | −236.8 to 132.0 | |||

n | Normal distribution | t test | −1.676 to 0.3118 | |||

o | Normal distribution | t test with Holm–Sidak for multiple comparisons | −33.97 to −22.24 | |||

p | Normal distribution | t test with Holm–Sidak for multiple comparisons | −33.59 to −21.85 | |||

q | Normal distribution | t test with Holm–Sidak for multiple comparisons | −31.04 to −19.30 | |||

r | Normal distribution | t test with Holm–Sidak for multiple comparisons | −29.59 to −17.86 | |||

s | Normal distribution | t test with Holm–Sidak for multiple comparisons | −30.39 to −18.66 | |||

t | Normal distribution | t test with Holm–Sidak for multiple comparisons | −27.73 to −16.00 | |||

u | Normal distribution | t test with Holm–Sidak for multiple comparisons | −18.01 to −6.278 | |||

v | Normal distribution | t test with Holm–Sidak for multiple comparisons | −24.10 to −12.37 | |||

w | Normal distribution | t test with Holm–Sidak for multiple comparisons | −26.07 to −14.33 | |||

x | Normal distribution | t test with Holm–Sidak for multiple comparisons | −29.68 to −17.95 | |||

y | Normal distribution | t test with Holm–Sidak for multiple comparisons | −26.95 to −15.21 | |||

z | Normal distribution | t test with Holm–Sidak for multiple comparisons | −27.74 to −16.01 | |||

aa | Normal distribution | t test | −116.0 to −98.31 | |||

bb | Normal distribution | t test with Holm–Sidak for multiple comparisons | −112.2 to −6.900 | |||

cc | Normal distribution | t test with Holm–Sidak for multiple comparisons | −128.0 to −22.77 | |||

dd | Normal distribution | t test with Holm–Sidak for multiple comparisons | −122.9 to −17.64 | |||

ee | Normal distribution | One-way ANOVA | Control vs 10 μm | −3.649 to 7.982 | ||

Control vs 50 μm | −6.585 to 5.046 | |||||

Control vs 100 μm | −4.812 to 6.819 | |||||

Control vs 1 mm | −6.324 to 5.307 | |||||

Control vs 4 mM | −7.943 to 2.825 | |||||

ff | Normal distribution | One-way ANOVA | Control vs 10 μm | −67.77 to 93.79 | ||

Control vs 50 μm | −62.06 to 99.49 | |||||

Control vs 100 μm | −39.08 to 122.5 | |||||

Control vs 1 mm | −19.22 to 142.3 | |||||

Control vs 4 mm | −19.85 to 129.7 | |||||

gg | Normal distribution | One-way ANOVA | WT vs WT+4-AP | −0.9128 to 0.1422 | ||

WT vs scn1Lab | −0.5763 to 0.4787 | |||||

WT vs scn1Lab+4-AP | −0.5664 to 0.4886 | |||||

hh | Normal distribution | Two-way ANOVA | Complex I | −148.8 to 112.6 | ||

Complex II | −138.4 to 123.1 | |||||

Complex III | −177.9 to 83.56 | |||||

Complex IV | −146.6 to 114.9 | |||||

ii | Normal distribution | Two-way ANOVA | Aconitase | −15.04 to 45.86 | ||

Fumarase | −32.52 to 28.38 | |||||

Mal. Dehyd. | −21.06 to 33.41 | |||||

jj | Normal distribution | t test | 1.783 to 8.531 | |||

kk | Normal distribution | t test | −4.128 to −2.727 | |||

ll | Normal distribution | t test | −36.51 to −22.87 | |||

mm | Normal distribution | t test | −98.59 to −32.08 | |||

nn | Normal distribution | t test | −104.4 to −49.14 | |||

oo | Normal distribution | t test | −46.07 to −30.43 | |||

pp | Normal distribution | t test | −52.57 to −32.94 | |||

Normal distribution | t test | −35.93 to −11.69 | ||||

rr | Normal distribution | t test | −32.95 to −15.50 |