Table 1:

Statistics

Data structureType of testPower
Figure 2A Increased proBDNF 3 h post-SE (HA immunoreactivity)Normal distributionStudent’s t test0.9775
Figure 2B Increased proBDNF 24 h post-SE (HA immunoreactivity)Normal distributionStudent’s t test0.9917
Figure 3A Increased proBDNF 3 h post-SE (commercial BDNF antibodies)Normal distributionStudent’s t test1.0000
Figure 3B Increased proBDNF 24 h post-SE (commercial BDNF antibodies)Normal distributionStudent’s t test0.9104
Figure 5A No change in furin 3 h post-SENormal distributionStudent’s t test0.0511
Figure 5B Significant increase in furin 24 h post-SENormal distributionStudent’s t test0.9198
Figure 5C No change in plasminogen 3 h post-SENormal distributionStudent’s t test0.5067
Figure 5D No change in plasminogen 24 h post-SENormal distributionStudent’s t test0.6526
Figure 5E No change in MMP-9 3 h post-SENormal distributionStudent’s t test0.1905
Figure 5F No change in MMP-9 24 h post-SENormal distributionStudent’s t test0.2765
Figure 5G Significant reduction in tPA 3 h post-SENormal distributionStudent’s t test0.9394
Figure 5H Significant reduction in tPA 24 h post-SENormal distributionStudent’s t test1.0000
Figure 6A No change in A2AP 3 h post-SENormal distributionStudent’s t test0.5646
Figure 6B No change in A2AP 24 h post-SENormal distributionStudent’s t test0.1068
Figure 6C Reduction in neuroserpin at 3 h post-SENormal distributionStudent’s t test0.9961
Figure 6D No change in neuroserpin at 24 h post-SENormal distributionStudent’s t test0.0744
Figure 6E No change in 23 kDa nonglycosylated TIMP-1 at 3 h post-SENormal distributionStudent’s t test0.1867
Figure 6E No change in 28 kDa glycosylated TIMP-1 at 3 h post-SENormal distributionStudent’s t test0.5007
Figure 6F No change in 23 kDa nonglycosylated TIMP-1 at 24 h post-SENormal distributionStudent’s t test0.6078
Figure 6F Significant reduction in 28 kDa glycosylated TIMP-1 at 24 h post-SENormal distributionStudent’s t test0.9987
Figure 6G Significant increase in PAI-1 at 3 h post-SENormal distributionStudent’s t test0.9601
Figure 6H Significant increase in PAI-1 at 24 h post-SENormal distributionStudent’s t test1.0000
Figure 7A Increased proBDNF 3 d post-SE (commercial BDNF antibodies)Normal distributionStudent’s t test0.971
Figure 7A Increased proBDNF 7 d post-SE (commercial BDNF antibodies)Normal distributionStudent’s t test1.000
Figure 7B Increased PAI-1 3 d post-SE (commercial BDNF antibodies)Non-normal distributionMann–Whitney testN/A
Figure 7B No change in PAI-1 7 d post-SE (commercial BDNF antibodies)Normal distributionStudent’s t test0.985
Figure 7C No change in tPA 3 d post-SE (commercial BDNF antibodies)Normal distributionStudent’s t test0.981
Figure 7C Increased tPA 7 d post-SE (commercial BDNF antibodies)Normal distributionStudent’s t test1.000
Figure 8 PAI-1 inhibition reduces proBDNF levels after pilocarpine SEN/APaired t test0.995